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Prevention of dsRNA‐induced interferon signaling by AGO1x is linked to breast cancer cell proliferation

Translational readthrough, i.e., elongation of polypeptide chains beyond the stop codon, was initially reported for viral RNA, but later found also on eukaryotic transcripts, resulting in proteome diversification and protein‐level modulation. Here, we report that AGO1x, an evolutionarily conserved t...

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Detalles Bibliográficos
Autores principales: Ghosh, Souvik, Guimaraes, Joao C, Lanzafame, Manuela, Schmidt, Alexander, Syed, Afzal Pasha, Dimitriades, Beatrice, Börsch, Anastasiya, Ghosh, Shreemoyee, Mittal, Nitish, Montavon, Thomas, Correia, Ana Luisa, Danner, Johannes, Meister, Gunter, Terracciano, Luigi M, Pfeffer, Sébastien, Piscuoglio, Salvatore, Zavolan, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507497/
https://www.ncbi.nlm.nih.gov/pubmed/32812257
http://dx.doi.org/10.15252/embj.2019103922