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The NRF2 stimulating agent, tin protoporphyrin, activates protective cytokine pathways in healthy human subjects and in patients with chronic kidney disease
BACKGROUND: Tin protoporphyrin (SnPP), a heme oxygenase 1 (HO‐1) inhibitor, triggers adaptive tissue responses that confer potent protection against acute renal‐ and extra‐renal tissue injuries. This effect is mediated, in part, via SnPP‐induced activation of the cytoprotective Nrf2 pathway. However...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507518/ https://www.ncbi.nlm.nih.gov/pubmed/32940965 http://dx.doi.org/10.14814/phy2.14566 |