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Irisin attenuates myocardial ischemia/reperfusion‐induced cardiac dysfunction by regulating ER‐mitochondria interaction through a mitochondrial ubiquitin ligase‐dependent mechanism

BACKGROUND: Myocardial ischemia/reperfusion (MI/R) injury imposes devastating cardiovascular sequelae in particular cardiac dysfunction as a result of restored blood flow. However, the mechanism behind MI/R injury remains elusive. Mitochondrial ubiquitin ligase (MITOL/MARCH5) is localized at the mit...

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Detalles Bibliográficos
Autores principales:	Lu, Linhe, Ma, Jipeng, Tang, Jiayou, Liu, Yang, Zheng, Qijun, Chen, Shasha, Gao, Erhe, Ren, Jun, Yang, Lifang, Yang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507588/ https://www.ncbi.nlm.nih.gov/pubmed/32997406 http://dx.doi.org/10.1002/ctm2.166

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