Whole-exome sequencing reveals potential mechanisms of drug resistance to FGFR3-TACC3 targeted therapy and subsequent drug selection: towards a personalized medicine

BACKGROUND: Drug resistance is a major obstacle to effective cancer therapy. In order to detect the change in tumor genomic states under drug selection pressure, we use next-generation sequencing technology to investigate the underlying potential mechanisms of drug resistance. METHODS: In our study,...

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Detalles Bibliográficos
Autores principales: Tong, Zhou, Yan, Cong, Dong, Yu-An, Yao, Ming, Zhang, Hangyu, Liu, Lulu, Zheng, Yi, Zhao, Peng, Wang, Yimin, Fang, Weijia, Zhang, Feifei, Jiang, Weiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507681/
https://www.ncbi.nlm.nih.gov/pubmed/32957974
http://dx.doi.org/10.1186/s12920-020-00794-x

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