Disseminated form of the Kaposi sarcoma in HIV-negative patient associated with Hodgkin’s lymphoma

We report a case of a 35-year-old, non-HIV-infected male diagnosed simultaneously with a disseminated form of Kaposi’s sarcoma (KS; skin, stomach and colon are involved) and Hodgkin’s lymphoma. There is no sign of changes in the immune status, but three herpes viruses were detected in the patient’s...

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Autores principales: Tutaeva, V V, Bobin, A N, Ovsiannikova, M R, Bulgakova, M V, Kuchma, Y M, Kryukov, E V, Rukavitsyn, O A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507874/
https://www.ncbi.nlm.nih.gov/pubmed/32995025
http://dx.doi.org/10.1093/omcr/omaa069
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author Tutaeva, V V
Bobin, A N
Ovsiannikova, M R
Bulgakova, M V
Kuchma, Y M
Kryukov, E V
Rukavitsyn, O A
author_facet Tutaeva, V V
Bobin, A N
Ovsiannikova, M R
Bulgakova, M V
Kuchma, Y M
Kryukov, E V
Rukavitsyn, O A
author_sort Tutaeva, V V
collection PubMed
description We report a case of a 35-year-old, non-HIV-infected male diagnosed simultaneously with a disseminated form of Kaposi’s sarcoma (KS; skin, stomach and colon are involved) and Hodgkin’s lymphoma. There is no sign of changes in the immune status, but three herpes viruses were detected in the patient’s blood (EBV, HHV6 and HHV8). He received ABVD chemotherapy and achieved complete metabolic remission for Hodgkin’s lymphoma. Moreover, the signs of the disseminated KS were resolved. Our observations indicate that a combination of distinct types of viruses may play an important role in triggering the development of angio- and lymphoproliferative disorders in the same person. In addition, treatment with chemotherapy cycles, which included doxorubicin and vinblastine, led to the stable remission of both diseases.
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spelling pubmed-75078742020-09-28 Disseminated form of the Kaposi sarcoma in HIV-negative patient associated with Hodgkin’s lymphoma Tutaeva, V V Bobin, A N Ovsiannikova, M R Bulgakova, M V Kuchma, Y M Kryukov, E V Rukavitsyn, O A Oxf Med Case Reports Case Report We report a case of a 35-year-old, non-HIV-infected male diagnosed simultaneously with a disseminated form of Kaposi’s sarcoma (KS; skin, stomach and colon are involved) and Hodgkin’s lymphoma. There is no sign of changes in the immune status, but three herpes viruses were detected in the patient’s blood (EBV, HHV6 and HHV8). He received ABVD chemotherapy and achieved complete metabolic remission for Hodgkin’s lymphoma. Moreover, the signs of the disseminated KS were resolved. Our observations indicate that a combination of distinct types of viruses may play an important role in triggering the development of angio- and lymphoproliferative disorders in the same person. In addition, treatment with chemotherapy cycles, which included doxorubicin and vinblastine, led to the stable remission of both diseases. Oxford University Press 2020-09-22 /pmc/articles/PMC7507874/ /pubmed/32995025 http://dx.doi.org/10.1093/omcr/omaa069 Text en © The Author(s) 2020. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Tutaeva, V V
Bobin, A N
Ovsiannikova, M R
Bulgakova, M V
Kuchma, Y M
Kryukov, E V
Rukavitsyn, O A
Disseminated form of the Kaposi sarcoma in HIV-negative patient associated with Hodgkin’s lymphoma
title Disseminated form of the Kaposi sarcoma in HIV-negative patient associated with Hodgkin’s lymphoma
title_full Disseminated form of the Kaposi sarcoma in HIV-negative patient associated with Hodgkin’s lymphoma
title_fullStr Disseminated form of the Kaposi sarcoma in HIV-negative patient associated with Hodgkin’s lymphoma
title_full_unstemmed Disseminated form of the Kaposi sarcoma in HIV-negative patient associated with Hodgkin’s lymphoma
title_short Disseminated form of the Kaposi sarcoma in HIV-negative patient associated with Hodgkin’s lymphoma
title_sort disseminated form of the kaposi sarcoma in hiv-negative patient associated with hodgkin’s lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507874/
https://www.ncbi.nlm.nih.gov/pubmed/32995025
http://dx.doi.org/10.1093/omcr/omaa069
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