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Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter?
BACKGROUND: The impact of clinician specialty on cardiovascular disease risk factor outcomes among persons with HIV (PWH) is unclear. METHODS: PWH receiving care at 3 Southeastern US academic HIV clinics between January 2014 and December 2016 were retrospectively stratified into 5 groups based on th...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507875/ https://www.ncbi.nlm.nih.gov/pubmed/32995348 http://dx.doi.org/10.1093/ofid/ofaa361 |
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author | Okeke, Nwora Lance Schafer, Katherine R Meissner, Eric G Ostermann, Jan Shah, Ansal D Ostasiewski, Brian Phelps, Evan Kieler, Curtis A Oladele, Eniola Garg, Keva Naggie, Susanna Bloomfield, Gerald S Bosworth, Hayden B |
author_facet | Okeke, Nwora Lance Schafer, Katherine R Meissner, Eric G Ostermann, Jan Shah, Ansal D Ostasiewski, Brian Phelps, Evan Kieler, Curtis A Oladele, Eniola Garg, Keva Naggie, Susanna Bloomfield, Gerald S Bosworth, Hayden B |
author_sort | Okeke, Nwora Lance |
collection | PubMed |
description | BACKGROUND: The impact of clinician specialty on cardiovascular disease risk factor outcomes among persons with HIV (PWH) is unclear. METHODS: PWH receiving care at 3 Southeastern US academic HIV clinics between January 2014 and December 2016 were retrospectively stratified into 5 groups based on the specialty of the clinician managing their hypertension or hyperlipidemia. Patients were followed until first atherosclerotic cardiovascular disease event, death, or end of study. Outcomes of interest were meeting 8th Joint National Commission (JNC-8) blood pressure (BP) goals and National Lipid Association (NLA) non–high-density lipoprotein (HDL) goals for hypertension and hyperlipidemia, respectively. Point estimates for associated risk factors were generated using modified Poisson regression with robust error variance. RESULTS: Of 1667 PWH in the analysis, 965 had hypertension, 205 had hyperlipidemia, and 497 had both diagnoses. At study start, the median patient age was 52 years, 66% were Black, and 65% identified as male. Among persons with hypertension, 24% were managed by an infectious diseases (ID) clinician alone, and 5% were co-managed by an ID clinician and a primary care clinician (PCC). Persons managed by an ID clinician were less likely to meet JNC-8 hypertension targets at the end of observation than the rest of the cohort (relative risk [RR], 0.84; 95% CI, 0.75–0.95), but when mean study blood pressure was considered, there was no difference between persons managed by ID and the rest of the cohort (RR, 0.96; 95% CI, 0.88–1.05). There was no significant association between the ID clinician managing hyperlipidemia and meeting NLA non-HDL goals (RR, 0.89; 95% CI, 0.68–1.15). CONCLUSIONS: Clinician specialty may play a role in suboptimal hypertension outcomes in persons with HIV. |
format | Online Article Text |
id | pubmed-7507875 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-75078752020-09-28 Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter? Okeke, Nwora Lance Schafer, Katherine R Meissner, Eric G Ostermann, Jan Shah, Ansal D Ostasiewski, Brian Phelps, Evan Kieler, Curtis A Oladele, Eniola Garg, Keva Naggie, Susanna Bloomfield, Gerald S Bosworth, Hayden B Open Forum Infect Dis Major Articles BACKGROUND: The impact of clinician specialty on cardiovascular disease risk factor outcomes among persons with HIV (PWH) is unclear. METHODS: PWH receiving care at 3 Southeastern US academic HIV clinics between January 2014 and December 2016 were retrospectively stratified into 5 groups based on the specialty of the clinician managing their hypertension or hyperlipidemia. Patients were followed until first atherosclerotic cardiovascular disease event, death, or end of study. Outcomes of interest were meeting 8th Joint National Commission (JNC-8) blood pressure (BP) goals and National Lipid Association (NLA) non–high-density lipoprotein (HDL) goals for hypertension and hyperlipidemia, respectively. Point estimates for associated risk factors were generated using modified Poisson regression with robust error variance. RESULTS: Of 1667 PWH in the analysis, 965 had hypertension, 205 had hyperlipidemia, and 497 had both diagnoses. At study start, the median patient age was 52 years, 66% were Black, and 65% identified as male. Among persons with hypertension, 24% were managed by an infectious diseases (ID) clinician alone, and 5% were co-managed by an ID clinician and a primary care clinician (PCC). Persons managed by an ID clinician were less likely to meet JNC-8 hypertension targets at the end of observation than the rest of the cohort (relative risk [RR], 0.84; 95% CI, 0.75–0.95), but when mean study blood pressure was considered, there was no difference between persons managed by ID and the rest of the cohort (RR, 0.96; 95% CI, 0.88–1.05). There was no significant association between the ID clinician managing hyperlipidemia and meeting NLA non-HDL goals (RR, 0.89; 95% CI, 0.68–1.15). CONCLUSIONS: Clinician specialty may play a role in suboptimal hypertension outcomes in persons with HIV. Oxford University Press 2020-08-21 /pmc/articles/PMC7507875/ /pubmed/32995348 http://dx.doi.org/10.1093/ofid/ofaa361 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Major Articles Okeke, Nwora Lance Schafer, Katherine R Meissner, Eric G Ostermann, Jan Shah, Ansal D Ostasiewski, Brian Phelps, Evan Kieler, Curtis A Oladele, Eniola Garg, Keva Naggie, Susanna Bloomfield, Gerald S Bosworth, Hayden B Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter? |
title | Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter? |
title_full | Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter? |
title_fullStr | Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter? |
title_full_unstemmed | Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter? |
title_short | Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter? |
title_sort | cardiovascular disease risk management in persons with hiv: does clinician specialty matter? |
topic | Major Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507875/ https://www.ncbi.nlm.nih.gov/pubmed/32995348 http://dx.doi.org/10.1093/ofid/ofaa361 |
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