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Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter?

BACKGROUND: The impact of clinician specialty on cardiovascular disease risk factor outcomes among persons with HIV (PWH) is unclear. METHODS: PWH receiving care at 3 Southeastern US academic HIV clinics between January 2014 and December 2016 were retrospectively stratified into 5 groups based on th...

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Autores principales: Okeke, Nwora Lance, Schafer, Katherine R, Meissner, Eric G, Ostermann, Jan, Shah, Ansal D, Ostasiewski, Brian, Phelps, Evan, Kieler, Curtis A, Oladele, Eniola, Garg, Keva, Naggie, Susanna, Bloomfield, Gerald S, Bosworth, Hayden B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507875/
https://www.ncbi.nlm.nih.gov/pubmed/32995348
http://dx.doi.org/10.1093/ofid/ofaa361
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author Okeke, Nwora Lance
Schafer, Katherine R
Meissner, Eric G
Ostermann, Jan
Shah, Ansal D
Ostasiewski, Brian
Phelps, Evan
Kieler, Curtis A
Oladele, Eniola
Garg, Keva
Naggie, Susanna
Bloomfield, Gerald S
Bosworth, Hayden B
author_facet Okeke, Nwora Lance
Schafer, Katherine R
Meissner, Eric G
Ostermann, Jan
Shah, Ansal D
Ostasiewski, Brian
Phelps, Evan
Kieler, Curtis A
Oladele, Eniola
Garg, Keva
Naggie, Susanna
Bloomfield, Gerald S
Bosworth, Hayden B
author_sort Okeke, Nwora Lance
collection PubMed
description BACKGROUND: The impact of clinician specialty on cardiovascular disease risk factor outcomes among persons with HIV (PWH) is unclear. METHODS: PWH receiving care at 3 Southeastern US academic HIV clinics between January 2014 and December 2016 were retrospectively stratified into 5 groups based on the specialty of the clinician managing their hypertension or hyperlipidemia. Patients were followed until first atherosclerotic cardiovascular disease event, death, or end of study. Outcomes of interest were meeting 8th Joint National Commission (JNC-8) blood pressure (BP) goals and National Lipid Association (NLA) non–high-density lipoprotein (HDL) goals for hypertension and hyperlipidemia, respectively. Point estimates for associated risk factors were generated using modified Poisson regression with robust error variance. RESULTS: Of 1667 PWH in the analysis, 965 had hypertension, 205 had hyperlipidemia, and 497 had both diagnoses. At study start, the median patient age was 52 years, 66% were Black, and 65% identified as male. Among persons with hypertension, 24% were managed by an infectious diseases (ID) clinician alone, and 5% were co-managed by an ID clinician and a primary care clinician (PCC). Persons managed by an ID clinician were less likely to meet JNC-8 hypertension targets at the end of observation than the rest of the cohort (relative risk [RR], 0.84; 95% CI, 0.75–0.95), but when mean study blood pressure was considered, there was no difference between persons managed by ID and the rest of the cohort (RR, 0.96; 95% CI, 0.88–1.05). There was no significant association between the ID clinician managing hyperlipidemia and meeting NLA non-HDL goals (RR, 0.89; 95% CI, 0.68–1.15). CONCLUSIONS: Clinician specialty may play a role in suboptimal hypertension outcomes in persons with HIV.
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spelling pubmed-75078752020-09-28 Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter? Okeke, Nwora Lance Schafer, Katherine R Meissner, Eric G Ostermann, Jan Shah, Ansal D Ostasiewski, Brian Phelps, Evan Kieler, Curtis A Oladele, Eniola Garg, Keva Naggie, Susanna Bloomfield, Gerald S Bosworth, Hayden B Open Forum Infect Dis Major Articles BACKGROUND: The impact of clinician specialty on cardiovascular disease risk factor outcomes among persons with HIV (PWH) is unclear. METHODS: PWH receiving care at 3 Southeastern US academic HIV clinics between January 2014 and December 2016 were retrospectively stratified into 5 groups based on the specialty of the clinician managing their hypertension or hyperlipidemia. Patients were followed until first atherosclerotic cardiovascular disease event, death, or end of study. Outcomes of interest were meeting 8th Joint National Commission (JNC-8) blood pressure (BP) goals and National Lipid Association (NLA) non–high-density lipoprotein (HDL) goals for hypertension and hyperlipidemia, respectively. Point estimates for associated risk factors were generated using modified Poisson regression with robust error variance. RESULTS: Of 1667 PWH in the analysis, 965 had hypertension, 205 had hyperlipidemia, and 497 had both diagnoses. At study start, the median patient age was 52 years, 66% were Black, and 65% identified as male. Among persons with hypertension, 24% were managed by an infectious diseases (ID) clinician alone, and 5% were co-managed by an ID clinician and a primary care clinician (PCC). Persons managed by an ID clinician were less likely to meet JNC-8 hypertension targets at the end of observation than the rest of the cohort (relative risk [RR], 0.84; 95% CI, 0.75–0.95), but when mean study blood pressure was considered, there was no difference between persons managed by ID and the rest of the cohort (RR, 0.96; 95% CI, 0.88–1.05). There was no significant association between the ID clinician managing hyperlipidemia and meeting NLA non-HDL goals (RR, 0.89; 95% CI, 0.68–1.15). CONCLUSIONS: Clinician specialty may play a role in suboptimal hypertension outcomes in persons with HIV. Oxford University Press 2020-08-21 /pmc/articles/PMC7507875/ /pubmed/32995348 http://dx.doi.org/10.1093/ofid/ofaa361 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Major Articles
Okeke, Nwora Lance
Schafer, Katherine R
Meissner, Eric G
Ostermann, Jan
Shah, Ansal D
Ostasiewski, Brian
Phelps, Evan
Kieler, Curtis A
Oladele, Eniola
Garg, Keva
Naggie, Susanna
Bloomfield, Gerald S
Bosworth, Hayden B
Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter?
title Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter?
title_full Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter?
title_fullStr Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter?
title_full_unstemmed Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter?
title_short Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter?
title_sort cardiovascular disease risk management in persons with hiv: does clinician specialty matter?
topic Major Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507875/
https://www.ncbi.nlm.nih.gov/pubmed/32995348
http://dx.doi.org/10.1093/ofid/ofaa361
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