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Trends in the Treatment Outcomes and Features of Cryptorchidism in Boys: A Single-Institute Experience

PURPOSE: Cryptorchidism is one of the most common congenital abnormalities in pediatric urology, and orchiopexy is performed for the prevention of testicular damage and malignant transformation. We examined the distribution and outcomes of cryptorchidism under a single investigator at our institute....

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Autores principales: Hori, Shunta, Aoki, Katsuya, Nishimura, Nobutaka, Morizawa, Yosuke, Gotoh, Daisuke, Fukui, Shinji, Nakai, Yasushi, Miyake, Makito, Torimoto, Kazumasa, Fujimoto, Kiyohide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508029/
https://www.ncbi.nlm.nih.gov/pubmed/32984085
http://dx.doi.org/10.2147/RRU.S271869
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author Hori, Shunta
Aoki, Katsuya
Nishimura, Nobutaka
Morizawa, Yosuke
Gotoh, Daisuke
Fukui, Shinji
Nakai, Yasushi
Miyake, Makito
Torimoto, Kazumasa
Fujimoto, Kiyohide
author_facet Hori, Shunta
Aoki, Katsuya
Nishimura, Nobutaka
Morizawa, Yosuke
Gotoh, Daisuke
Fukui, Shinji
Nakai, Yasushi
Miyake, Makito
Torimoto, Kazumasa
Fujimoto, Kiyohide
author_sort Hori, Shunta
collection PubMed
description PURPOSE: Cryptorchidism is one of the most common congenital abnormalities in pediatric urology, and orchiopexy is performed for the prevention of testicular damage and malignant transformation. We examined the distribution and outcomes of cryptorchidism under a single investigator at our institute. PATIENTS AND METHODS: This retrospective study included 283 boys diagnosed with cryptorchidism at our institute. Cryptorchidism was diagnosed based on the medical history and physical examination findings. Boys without spontaneous resolution after 6 months of age were indicated for orchiopexy. We investigated the 12-year trend in the distribution and outcomes of cryptorchidism at the institute. RESULTS: The mean age at diagnosis, gestational age, and birth weight were 2 years, 37 weeks, and 2740 g, respectively. A total of 170 boys underwent orchiopexy under 2 years of age, and 136 boys underwent orchiopexy under the age of 1 year, while 62 boys underwent orchiopexy over the age of 3 years. Abnormalities of the epididymis and disclosure of the processus vaginalis were observed in 44 (25%) and 72 boys (41%), respectively. Comparison of boys with or without hypospadias showed that the age at orchiopexy was higher in boys with hypospadias than in those without hypospadias (P=0.028). In addition, boys without hypospadias had a higher rate of abnormality of the epidermis than those with hypospadias (P=0.024). CONCLUSION: Our findings suggest that most boys with cryptorchidism are treated under the age of 2 years and the incidence of epididymal abnormality is relatively high, especially in boys with hypospadias. An understanding of the natural features of cryptorchidism could lead to better management and outcomes. Further research is warranted to develop an appropriate treatment timeline in boys with cryptorchidism.
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spelling pubmed-75080292020-09-24 Trends in the Treatment Outcomes and Features of Cryptorchidism in Boys: A Single-Institute Experience Hori, Shunta Aoki, Katsuya Nishimura, Nobutaka Morizawa, Yosuke Gotoh, Daisuke Fukui, Shinji Nakai, Yasushi Miyake, Makito Torimoto, Kazumasa Fujimoto, Kiyohide Res Rep Urol Original Research PURPOSE: Cryptorchidism is one of the most common congenital abnormalities in pediatric urology, and orchiopexy is performed for the prevention of testicular damage and malignant transformation. We examined the distribution and outcomes of cryptorchidism under a single investigator at our institute. PATIENTS AND METHODS: This retrospective study included 283 boys diagnosed with cryptorchidism at our institute. Cryptorchidism was diagnosed based on the medical history and physical examination findings. Boys without spontaneous resolution after 6 months of age were indicated for orchiopexy. We investigated the 12-year trend in the distribution and outcomes of cryptorchidism at the institute. RESULTS: The mean age at diagnosis, gestational age, and birth weight were 2 years, 37 weeks, and 2740 g, respectively. A total of 170 boys underwent orchiopexy under 2 years of age, and 136 boys underwent orchiopexy under the age of 1 year, while 62 boys underwent orchiopexy over the age of 3 years. Abnormalities of the epididymis and disclosure of the processus vaginalis were observed in 44 (25%) and 72 boys (41%), respectively. Comparison of boys with or without hypospadias showed that the age at orchiopexy was higher in boys with hypospadias than in those without hypospadias (P=0.028). In addition, boys without hypospadias had a higher rate of abnormality of the epidermis than those with hypospadias (P=0.024). CONCLUSION: Our findings suggest that most boys with cryptorchidism are treated under the age of 2 years and the incidence of epididymal abnormality is relatively high, especially in boys with hypospadias. An understanding of the natural features of cryptorchidism could lead to better management and outcomes. Further research is warranted to develop an appropriate treatment timeline in boys with cryptorchidism. Dove 2020-09-14 /pmc/articles/PMC7508029/ /pubmed/32984085 http://dx.doi.org/10.2147/RRU.S271869 Text en © 2020 Hori et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Hori, Shunta
Aoki, Katsuya
Nishimura, Nobutaka
Morizawa, Yosuke
Gotoh, Daisuke
Fukui, Shinji
Nakai, Yasushi
Miyake, Makito
Torimoto, Kazumasa
Fujimoto, Kiyohide
Trends in the Treatment Outcomes and Features of Cryptorchidism in Boys: A Single-Institute Experience
title Trends in the Treatment Outcomes and Features of Cryptorchidism in Boys: A Single-Institute Experience
title_full Trends in the Treatment Outcomes and Features of Cryptorchidism in Boys: A Single-Institute Experience
title_fullStr Trends in the Treatment Outcomes and Features of Cryptorchidism in Boys: A Single-Institute Experience
title_full_unstemmed Trends in the Treatment Outcomes and Features of Cryptorchidism in Boys: A Single-Institute Experience
title_short Trends in the Treatment Outcomes and Features of Cryptorchidism in Boys: A Single-Institute Experience
title_sort trends in the treatment outcomes and features of cryptorchidism in boys: a single-institute experience
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508029/
https://www.ncbi.nlm.nih.gov/pubmed/32984085
http://dx.doi.org/10.2147/RRU.S271869
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