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Can genetics reveal the causes and consequences of educational attainment?

There is an extensive literature on the causes of educational inequalities, and the life course consequences of educational attainment. Mendelian randomization, where genetic variants associated with exposures of interest are used as proxies for those exposures, often within an instrumental variable...

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Detalles Bibliográficos
Autores principales: Munafò, Marcus, Davies, Neil M., Davey Smith, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508183/
https://www.ncbi.nlm.nih.gov/pubmed/32999534
http://dx.doi.org/10.1111/rssa.12543
Descripción
Sumario:There is an extensive literature on the causes of educational inequalities, and the life course consequences of educational attainment. Mendelian randomization, where genetic variants associated with exposures of interest are used as proxies for those exposures, often within an instrumental variables framework, has proven highly effective at elucidating the causal effects of several risk factors in the biomedical sciences. We discuss the potential for this approach to be used in the context of social and socio‐economic exposures and outcomes, such as educational attainment.