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Can genetics reveal the causes and consequences of educational attainment?

There is an extensive literature on the causes of educational inequalities, and the life course consequences of educational attainment. Mendelian randomization, where genetic variants associated with exposures of interest are used as proxies for those exposures, often within an instrumental variable...

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Detalles Bibliográficos
Autores principales: Munafò, Marcus, Davies, Neil M., Davey Smith, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508183/
https://www.ncbi.nlm.nih.gov/pubmed/32999534
http://dx.doi.org/10.1111/rssa.12543
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author Munafò, Marcus
Davies, Neil M.
Davey Smith, George
author_facet Munafò, Marcus
Davies, Neil M.
Davey Smith, George
author_sort Munafò, Marcus
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description There is an extensive literature on the causes of educational inequalities, and the life course consequences of educational attainment. Mendelian randomization, where genetic variants associated with exposures of interest are used as proxies for those exposures, often within an instrumental variables framework, has proven highly effective at elucidating the causal effects of several risk factors in the biomedical sciences. We discuss the potential for this approach to be used in the context of social and socio‐economic exposures and outcomes, such as educational attainment.
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spelling pubmed-75081832020-09-28 Can genetics reveal the causes and consequences of educational attainment? Munafò, Marcus Davies, Neil M. Davey Smith, George J R Stat Soc Ser A Stat Soc Original Articles There is an extensive literature on the causes of educational inequalities, and the life course consequences of educational attainment. Mendelian randomization, where genetic variants associated with exposures of interest are used as proxies for those exposures, often within an instrumental variables framework, has proven highly effective at elucidating the causal effects of several risk factors in the biomedical sciences. We discuss the potential for this approach to be used in the context of social and socio‐economic exposures and outcomes, such as educational attainment. John Wiley and Sons Inc. 2019-11-24 2020-02 /pmc/articles/PMC7508183/ /pubmed/32999534 http://dx.doi.org/10.1111/rssa.12543 Text en © 2019 The Authors Journal of the Royal Statistical Society: Series A (Statistics in Society) Published by John Wiley & Sons Ltd on behalf of the Royal Statistical Society. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Munafò, Marcus
Davies, Neil M.
Davey Smith, George
Can genetics reveal the causes and consequences of educational attainment?
title Can genetics reveal the causes and consequences of educational attainment?
title_full Can genetics reveal the causes and consequences of educational attainment?
title_fullStr Can genetics reveal the causes and consequences of educational attainment?
title_full_unstemmed Can genetics reveal the causes and consequences of educational attainment?
title_short Can genetics reveal the causes and consequences of educational attainment?
title_sort can genetics reveal the causes and consequences of educational attainment?
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508183/
https://www.ncbi.nlm.nih.gov/pubmed/32999534
http://dx.doi.org/10.1111/rssa.12543
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