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Pharmacologic Inhibition of Ezrin-Radixin-Moesin Phosphorylation is a Novel Therapeutic Strategy in Rhabdomyosarcoma

Intermediate and high-risk rhabdomyosarcoma (RMS) patients have poor prognosis with available treatment options, highlighting a clear unmet need for identification of novel therapeutic strategies. Ezrin-radixin-moesin (ERM) family members are membrane-cytoskeleton linker proteins with well-defined r...

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Detalles Bibliográficos
Autores principales: Proudfit, Austin, Bhunia, Nabanita, Pore, Debasis, Parker, Yvonne, Lindner, Daniel, Gupta, Neetu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508224/
https://www.ncbi.nlm.nih.gov/pubmed/33005093
http://dx.doi.org/10.1155/2020/9010496