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JAM-A Acts via C/EBP-α to Promote Claudin-5 Expression and Enhance Endothelial Barrier Function
RATIONALE: Intercellular tight junctions are crucial for correct regulation of the endothelial barrier. Their composition and integrity are affected in pathological contexts, such as inflammation and tumor growth. JAM-A (junctional adhesion molecule A) is a transmembrane component of tight junctions...
Autores principales: | Kakogiannos, Nikolaos, Ferrari, Laura, Giampietro, Costanza, Scalise, Anna Agata, Maderna, Claudio, Ravà, Micol, Taddei, Andrea, Lampugnani, Maria Grazia, Pisati, Federica, Malinverno, Matteo, Martini, Emanuele, Costa, Ilaria, Lupia, Michela, Cavallaro, Ugo, Beznoussenko, Galina V., Mironov, Alexander A., Fernandes, Bethania, Rudini, Noemi, Dejana, Elisabetta, Giannotta, Monica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508279/ https://www.ncbi.nlm.nih.gov/pubmed/32673519 http://dx.doi.org/10.1161/CIRCRESAHA.120.316742 |
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