Cargando…

Targeted Sequencing of Sorted Esophageal Adenocarcinoma Cells Unveils Known and Novel Mutations in the Separated Subpopulations

INTRODUCTION: Our study aimed at investigating tumor heterogeneity in esophageal adenocarcinoma (EAC) cells regarding clinical outcomes. METHODS: Thirty-eight surgical EAC cases who underwent gastroesophageal resection with lymph node dissection in 3 university centers were included. Archival materi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Isidori, Federica, Bozzarelli, Isotta, Mastracci, Luca, Malvi, Deborah, Lugaresi, Marialuisa, Molinari, Chiara, Söderström, Henna, Räsänen, Jari, D'Errico, Antonia, Fiocca, Roberto, Seri, Marco, Krishnadath, Kausilia K., Bonora, Elena, Mattioli, Sandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508445/ https://www.ncbi.nlm.nih.gov/pubmed/33094962 http://dx.doi.org/10.14309/ctg.0000000000000202

Ejemplares similares

Genomic profiles of primary and metastatic esophageal adenocarcinoma identified via digital sorting of pure cell populations: results from a case report
por: Isidori, Federica, et al.
Publicado: (2018)

Correlations between Molecular Alterations, Histopathological Characteristics, and Poor Prognosis in Esophageal Adenocarcinoma
por: Orsini, Arianna, et al.
Publicado: (2023)

The Prognostic Impact of Histology in Esophageal and Esophago-Gastric Junction Adenocarcinoma
por: Fiocca, Roberto, et al.
Publicado: (2021)

RASAL1 and ROS1 Gene Variants in Hereditary Breast Cancer
por: Isidori, Federica, et al.
Publicado: (2020)

Overexpression of HSP27 and HSP70 is associated with decreased survival among patients with esophageal adenocarcinoma
por: Söderström, Henna K, et al.
Publicado: (2019)

PerSort Facilitates Characterization and Elimination of Persister Subpopulation in Mycobacteria
por: Srinivas, Vivek, et al.
Publicado: (2020)

Detection of a Novel MSI2-C17orf64 Transcript in a Patient with Aggressive Adenocarcinoma of the Gastroesophageal Junction: A Case Report
por: Ferrari, Anna, et al.
Publicado: (2023)

Single domain Camelid antibody fragments for molecular imaging and therapy of cancer
por: Li, Shulin, et al.
Publicado: (2023)

Molecular Biology and Clinical Management of Esophageal Adenocarcinoma
por: Li, Shulin, et al.
Publicado: (2023)

Trastuzumab Mediated T-Cell Response against HER-2/Neu Overexpressing Esophageal Adenocarcinoma Depends on Intact Antigen Processing Machinery
por: Milano, Francesca, et al.
Publicado: (2010)

Protein characterization of intracellular target-sorted, formalin-fixed cell subpopulations
por: Sadick, Jessica S., et al.
Publicado: (2016)

Second Opinion in the Italian Organ Procurement Transplantation: The Pathologist Is In
por: Eccher, Albino, et al.
Publicado: (2023)

Novel In Vivo Mouse Cryoablation Model to Explore Unique Therapeutic Approaches for Premalignant Columnar Lesions
por: Correia, Ana C. P., et al.
Publicado: (2021)

Characterization of radiation resistant hypoxic cell subpopulations in KHT sarcomas. (II). Cell sorting.
por: Siemann, D. W., et al.
Publicado: (1988)

Lung fibrosis: an undervalued finding in COVID-19 pathological series
por: Grillo, Federica, et al.
Publicado: (2021)

Selective Vulnerability of Spinal and Cortical Motor Neuron Subpopulations in delta7 SMA Mice
por: d’Errico, Paolo, et al.
Publicado: (2013)

Comparison of newly developed anti-bone morphogenetic protein 4 llama-derived antibodies with commercially available BMP4 inhibitors
por: Calpe, Silvia, et al.
Publicado: (2016)

Challenging liver lesions in noncirrhotic patients: Report of three cases
por: Franceschini, Tania, et al.
Publicado: (2019)

Nano-Curcumin Inhibits Proliferation of Esophageal Adenocarcinoma Cells and Enhances the T Cell Mediated Immune Response
por: Milano, Francesca, et al.
Publicado: (2013)

Towards Personalized Treatment Strategies for Esophageal Adenocarcinoma; A Review on the Molecular Characterization of Esophageal Adenocarcinoma and Current Research Efforts on Individualized Curative Treatment Regimens
por: Hoefnagel, Sanne J. M., et al.
Publicado: (2021)

Inhibition of the BMP pathway prevents development of Barrett’s-associated adenocarcinoma in a surgical rat model
por: Westra, Wytske M, et al.
Publicado: (2021)

Selective targeting BMP2 and 4 in SMAD4 negative esophageal adenocarcinoma inhibits tumor growth and aggressiveness in preclinical models
por: Li, Shulin, et al.
Publicado: (2022)

Sorting of Golgi resident proteins into different subpopulations of COPI vesicles: a role for ArfGAP1
por: Lanoix, Joel, et al.
Publicado: (2001)

Unequivocal Identification of Subpopulations in Putative Multiclonal Trypanosoma cruzi Strains by FACs Single Cell Sorting and Genotyping
por: Valadares, Helder Magno Silva, et al.
Publicado: (2012)

Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans
por: Muñoz, José F., et al.
Publicado: (2019)

High accuracy gene expression profiling of sorted cell subpopulations from breast cancer PDX model tissue
por: Porter, Warren, et al.
Publicado: (2020)

Single cell qtSEQ: Cell-indexed quantitative and targeted RNA sequencing for sorted rare lymphocyte subpopulations
por: Shuparski, Andrew G., et al.
Publicado: (2021)

Validation of portable tablets for transplant pathology diagnosis according to the College of American Pathologists Guidelines
por: Marletta, Stefano, et al.
Publicado: (2022)

Fitting and Testing Log-Linear Subpopulation Models with Known Support
por: Hessen, David J.
Publicado: (2023)

Pathological features and outcomes of incidental renal cell carcinoma in candidate solid organ donors
por: Ambrosi, Francesca, et al.
Publicado: (2020)

Giant Filiform Polyposis not Associated with Inflammatory Bowel Disease: A Case Report
por: Ponte, Rossella, et al.
Publicado: (2015)

MicroRNA Expression can be a Promising Strategy for the Detection of Barrett's Esophagus: A Pilot Study
por: Bansal, Ajay, et al.
Publicado: (2014)

Genetic Abnormalities in Biliary Brush Samples for Distinguishing Cholangiocarcinoma from Benign Strictures in Primary Sclerosing Cholangitis
por: Timmer, Margriet R., et al.
Publicado: (2016)

Glyco-conjugated bile acids drive the initial metaplastic gland formation from multi-layered glands through crypt-fission in a murine model
por: Straub, Danielle, et al.
Publicado: (2019)

Improved Sensitivity in Comparative Genomic Hybridization Analysis of DNA Heteroploid Cell Mixtures after Pre-Enrichment of Subpopulations by Fluorescence Activated Cell Sorting
por: Larsen, Jacob, et al.
Publicado: (1999)

Cytometry meets next-generation sequencing – RNA-Seq of sorted subpopulations reveals regional replication and iron-triggered prophage induction in Corynebacterium glutamicum
por: Freiherr von Boeselager, Raphael, et al.
Publicado: (2018)

Gastritis: update on etiological features and histological practical approach
por: Pennelli, Gianmaria, et al.
Publicado: (2020)

Detection of circulating BMP5 as a risk factor for Barrett’s esophagus
por: Correia, Ana C. P., et al.
Publicado: (2020)

Minimum biopsy set for HER2 evaluation in gastric and gastro-esophageal junction cancer
por: Gullo, Irene, et al.
Publicado: (2015)

The Surgical Treatment of Hydrocephalus Associated with Spina Bifida
por: D'Errico, Albert
Publicado: (1939)

Cannot write session to /tmp/vufind_sessions/sess_qp8uqphqns65rm29je5lnf1bt2