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Clinical Characteristics and Postoperative Outcomes of Patients Presenting With Upper Gastrointestinal Tract Crohn Disease

PURPOSE: Upper gastrointestinal (GI) tract involvement in Crohn disease (CD) is rare and effectiveness of surgical treatment is limited. The aim of this study was to evaluate characteristics and surgical outcomes of upper GI CD. METHODS: Medical records of 811 patients who underwent intestinal surge...

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Autores principales: Moon, Joon Suk, Lee, Jong Lyul, Yu, Chang Sik, Lim, Seok-Byung, Park, In Ja, Yoon, Yong Sik, Kim, Chan Wook, Yang, Suk-Kyun, Ye, Byong Duk, Park, Sang Hyoung, Alsaleem, Hassan Abdullah, Kim, Jin Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Coloproctology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508485/
https://www.ncbi.nlm.nih.gov/pubmed/32178500
http://dx.doi.org/10.3393/ac.2019.10.16.1
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author Moon, Joon Suk
Lee, Jong Lyul
Yu, Chang Sik
Lim, Seok-Byung
Park, In Ja
Yoon, Yong Sik
Kim, Chan Wook
Yang, Suk-Kyun
Ye, Byong Duk
Park, Sang Hyoung
Alsaleem, Hassan Abdullah
Kim, Jin Cheon
author_facet Moon, Joon Suk
Lee, Jong Lyul
Yu, Chang Sik
Lim, Seok-Byung
Park, In Ja
Yoon, Yong Sik
Kim, Chan Wook
Yang, Suk-Kyun
Ye, Byong Duk
Park, Sang Hyoung
Alsaleem, Hassan Abdullah
Kim, Jin Cheon
author_sort Moon, Joon Suk
collection PubMed
description PURPOSE: Upper gastrointestinal (GI) tract involvement in Crohn disease (CD) is rare and effectiveness of surgical treatment is limited. The aim of this study was to evaluate characteristics and surgical outcomes of upper GI CD. METHODS: Medical records of 811 patients who underwent intestinal surgery for CD between January 2006 and December 2015 at a single institution were reviewed. Upper GI CD was defined by involvement of the stomach to the fourth portion of duodenum, with or without concomitant small/large bowel CD involvement according to a modification of the Montreal classification. RESULTS: We identified 24 patients (21 males, 3 females) who underwent surgery for upper GI CD. The mean age at diagnosis was 27 ± 12 years, the mean age at surgery was 33 ± 11 years, and the mean duration of CD was 73.6 ± 56.6 months. Fifteen patients (62.5%) had history of previous perianal surgery. Ten patients (41.7%) had duodenal or gastric stricture and 14 patients (58.3%) had penetrating fistula; patients with fistula were significantly more likely to develop complications (57.1% vs. 20.0%, P = 0.035). One patient with stricture had surgical recurrence. In seven patients with fistula, fistula was related to previous anastomosis. Patients with fistula had significantly longer hospital stays than those with stricture (16 days vs. 11 days, P = 0.01). CONCLUSION: Upper GI CD is rare among CD types (2.96%). In patients with upper GI CD, penetrating fistula was associated with longer hospital stay and more complications.
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spelling pubmed-75084852020-09-30 Clinical Characteristics and Postoperative Outcomes of Patients Presenting With Upper Gastrointestinal Tract Crohn Disease Moon, Joon Suk Lee, Jong Lyul Yu, Chang Sik Lim, Seok-Byung Park, In Ja Yoon, Yong Sik Kim, Chan Wook Yang, Suk-Kyun Ye, Byong Duk Park, Sang Hyoung Alsaleem, Hassan Abdullah Kim, Jin Cheon Ann Coloproctol Original Article PURPOSE: Upper gastrointestinal (GI) tract involvement in Crohn disease (CD) is rare and effectiveness of surgical treatment is limited. The aim of this study was to evaluate characteristics and surgical outcomes of upper GI CD. METHODS: Medical records of 811 patients who underwent intestinal surgery for CD between January 2006 and December 2015 at a single institution were reviewed. Upper GI CD was defined by involvement of the stomach to the fourth portion of duodenum, with or without concomitant small/large bowel CD involvement according to a modification of the Montreal classification. RESULTS: We identified 24 patients (21 males, 3 females) who underwent surgery for upper GI CD. The mean age at diagnosis was 27 ± 12 years, the mean age at surgery was 33 ± 11 years, and the mean duration of CD was 73.6 ± 56.6 months. Fifteen patients (62.5%) had history of previous perianal surgery. Ten patients (41.7%) had duodenal or gastric stricture and 14 patients (58.3%) had penetrating fistula; patients with fistula were significantly more likely to develop complications (57.1% vs. 20.0%, P = 0.035). One patient with stricture had surgical recurrence. In seven patients with fistula, fistula was related to previous anastomosis. Patients with fistula had significantly longer hospital stays than those with stricture (16 days vs. 11 days, P = 0.01). CONCLUSION: Upper GI CD is rare among CD types (2.96%). In patients with upper GI CD, penetrating fistula was associated with longer hospital stay and more complications. Korean Society of Coloproctology 2020-08 2020-03-16 /pmc/articles/PMC7508485/ /pubmed/32178500 http://dx.doi.org/10.3393/ac.2019.10.16.1 Text en Copyright © 2020 The Korean Society of Coloproctology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Moon, Joon Suk
Lee, Jong Lyul
Yu, Chang Sik
Lim, Seok-Byung
Park, In Ja
Yoon, Yong Sik
Kim, Chan Wook
Yang, Suk-Kyun
Ye, Byong Duk
Park, Sang Hyoung
Alsaleem, Hassan Abdullah
Kim, Jin Cheon
Clinical Characteristics and Postoperative Outcomes of Patients Presenting With Upper Gastrointestinal Tract Crohn Disease
title Clinical Characteristics and Postoperative Outcomes of Patients Presenting With Upper Gastrointestinal Tract Crohn Disease
title_full Clinical Characteristics and Postoperative Outcomes of Patients Presenting With Upper Gastrointestinal Tract Crohn Disease
title_fullStr Clinical Characteristics and Postoperative Outcomes of Patients Presenting With Upper Gastrointestinal Tract Crohn Disease
title_full_unstemmed Clinical Characteristics and Postoperative Outcomes of Patients Presenting With Upper Gastrointestinal Tract Crohn Disease
title_short Clinical Characteristics and Postoperative Outcomes of Patients Presenting With Upper Gastrointestinal Tract Crohn Disease
title_sort clinical characteristics and postoperative outcomes of patients presenting with upper gastrointestinal tract crohn disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508485/
https://www.ncbi.nlm.nih.gov/pubmed/32178500
http://dx.doi.org/10.3393/ac.2019.10.16.1
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