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Relationship between Gepotidacin Exposure and Prevention of On-Therapy Resistance Amplification in a Neisseria gonorrhoeae Hollow-Fiber In Vitro Infection Model

Multidrug-resistant Neisseria gonorrhoeae has emerged as a threat to global health. The relationship between gepotidacin exposure and prevention of on-therapy amplification of drug-resistant N. gonorrhoeae was examined using a 7-day hollow-fiber in vitro infection model. The study design included bo...

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Detalles Bibliográficos
Autores principales: VanScoy, Brian D., Scangarella-Oman, Nicole E., Fikes, Steven, Min, Sharon, Huang, Jianzhong, Ingraham, Karen, Bhavnani, Sujata M., Conde, Haley, Ambrose, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508576/
https://www.ncbi.nlm.nih.gov/pubmed/32661002
http://dx.doi.org/10.1128/AAC.00521-20

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