Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma

BACKGROUND: Gastrointestinal symptoms are not rare among coronavirus disease 2019 (COVID-19) patients, but there have been no reports regarding convalescent plasma therapy for the recovery of gastrointestinal problems in COVID-19 patients. CASE PRESENTATION: We present two cases of patients with COV...

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Autores principales: Zhang, Li-Bo, Pang, Rong-Rong, Qiao, Qing-Hua, Wang, Zhi-Hua, Xia, Xin-Yi, Wang, Chang-Jun, Xu, Xiao-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508641/
https://www.ncbi.nlm.nih.gov/pubmed/32962760
http://dx.doi.org/10.1186/s40779-020-00273-5
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author Zhang, Li-Bo
Pang, Rong-Rong
Qiao, Qing-Hua
Wang, Zhi-Hua
Xia, Xin-Yi
Wang, Chang-Jun
Xu, Xiao-Li
author_facet Zhang, Li-Bo
Pang, Rong-Rong
Qiao, Qing-Hua
Wang, Zhi-Hua
Xia, Xin-Yi
Wang, Chang-Jun
Xu, Xiao-Li
author_sort Zhang, Li-Bo
collection PubMed
description BACKGROUND: Gastrointestinal symptoms are not rare among coronavirus disease 2019 (COVID-19) patients, but there have been no reports regarding convalescent plasma therapy for the recovery of gastrointestinal problems in COVID-19 patients. CASE PRESENTATION: We present two cases of patients with COVID-19-associated recurrent diarrhea and positive fecal occult blood who successfully recovered after a one-time convalescent plasma administration. CONCLUSION: When COVID-19 patients develop recurrent or refractory gastrointestinal symptoms and fail to respond to the available treatment, alternative therapy with convalescent plasma administration may be considered.
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spelling pubmed-75086412020-09-23 Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma Zhang, Li-Bo Pang, Rong-Rong Qiao, Qing-Hua Wang, Zhi-Hua Xia, Xin-Yi Wang, Chang-Jun Xu, Xiao-Li Mil Med Res Case Report BACKGROUND: Gastrointestinal symptoms are not rare among coronavirus disease 2019 (COVID-19) patients, but there have been no reports regarding convalescent plasma therapy for the recovery of gastrointestinal problems in COVID-19 patients. CASE PRESENTATION: We present two cases of patients with COVID-19-associated recurrent diarrhea and positive fecal occult blood who successfully recovered after a one-time convalescent plasma administration. CONCLUSION: When COVID-19 patients develop recurrent or refractory gastrointestinal symptoms and fail to respond to the available treatment, alternative therapy with convalescent plasma administration may be considered. BioMed Central 2020-09-23 /pmc/articles/PMC7508641/ /pubmed/32962760 http://dx.doi.org/10.1186/s40779-020-00273-5 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Zhang, Li-Bo
Pang, Rong-Rong
Qiao, Qing-Hua
Wang, Zhi-Hua
Xia, Xin-Yi
Wang, Chang-Jun
Xu, Xiao-Li
Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma
title Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma
title_full Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma
title_fullStr Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma
title_full_unstemmed Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma
title_short Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma
title_sort successful recovery of covid-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508641/
https://www.ncbi.nlm.nih.gov/pubmed/32962760
http://dx.doi.org/10.1186/s40779-020-00273-5
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