Cargando…

Probing conformational transitions towards mutagenic Watson–Crick-like G·T mismatches using off-resonance sugar carbon R(1ρ) relaxation dispersion

NMR off-resonance R(1ρ) relaxation dispersion measurements on base carbon and nitrogen nuclei have revealed that wobble G·T/U mismatches in DNA and RNA duplexes exist in dynamic equilibrium with short-lived, low-abundance, and mutagenic Watson–Crick-like conformations. As Watson–Crick-like G·T misma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rangadurai, Atul, Szymanski, Eric S., Kimsey, Isaac, Shi, Honglue, Al-Hashimi, Hashim M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508749/ https://www.ncbi.nlm.nih.gov/pubmed/32789613 http://dx.doi.org/10.1007/s10858-020-00337-7

Ejemplares similares

Rapid assessment of Watson–Crick to Hoogsteen exchange in unlabeled DNA duplexes using high-power SELOPE imino (1)H CEST
por: Liu, Bei, et al.
Publicado: (2021)

Insights into Watson–Crick/Hoogsteen breathing dynamics and damage repair from the solution structure and dynamic ensemble of DNA duplexes containing m(1)A
por: Sathyamoorthy, Bharathwaj, et al.
Publicado: (2017)

5‐Oxyacetic Acid Modification Destabilizes Double Helical Stem Structures and Favors Anionic Watson–Crick like cmo(5)U‐G Base Pairs
por: Strebitzer, Elisabeth, et al.
Publicado: (2018)

A rule of seven in Watson-Crick base pairing of mismatched sequences
por: Cisse, Ibrahim I., et al.
Publicado: (2012)

Probing Watson-Crick and Hoogsteen base pairing in duplex DNA using dynamic nuclear polarization solid-state NMR spectroscopy
por: Conroy, Daniel W., et al.
Publicado: (2022)

Crick, Watson y el ADN
por: Strathern, Paul, 1940-
Publicado: (1999)

The multiple personalities of Watson and Crick strands
por: Cartwright, Reed A, et al.
Publicado: (2011)

An innate twist between Crick’s wobble and Watson-Crick base pairs
por: Ananth, Prakash, et al.
Publicado: (2013)

Accurate geometrical restraints for Watson–Crick base pairs
por: Gilski, Miroslaw, et al.
Publicado: (2019)

Non-dissociative structural transitions of the Watson-Crick and reverse Watson-Crick А·Т DNA base pairs into the Hoogsteen and reverse Hoogsteen forms
por: Brovarets’, Ol’ha O., et al.
Publicado: (2018)

Non-Watson–Crick RNA synthesis suited to origin functions
por: Puthenvedu, Deepa, et al.
Publicado: (2018)

Effect of loop length variation on quadruplex-Watson Crick duplex competition
por: Kumar, Niti, et al.
Publicado: (2008)

Atomistic insight into the kinetic pathways for Watson–Crick to Hoogsteen transitions in DNA
por: Vreede, Jocelyne, et al.
Publicado: (2019)

Measuring thermodynamic preferences to form non-native conformations in nucleic acids using ultraviolet melting
por: Rangadurai, Atul, et al.
Publicado: (2022)

Watson–Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation
por: Rypniewski, Wojciech, et al.
Publicado: (2016)

Crystallographic evidence of Watson–Crick connectivity in the base pair of anionic adenine with thymine
por: Mishra, Manish Kumar, et al.
Publicado: (2020)

Why are Hoogsteen base pairs energetically disfavored in A-RNA compared to B-DNA?
por: Rangadurai, Atul, et al.
Publicado: (2018)

Recognition of Watson-Crick base pairs: constraints and limits due to geometric selection and tautomerism
por: Westhof, Eric, et al.
Publicado: (2014)

Backbone-free duplex-stacked monomer nucleic acids exhibiting Watson–Crick selectivity
por: Smith, Gregory P., et al.
Publicado: (2018)

Multiscale Modeling of Wobble to Watson–Crick-Like Guanine–Uracil Tautomerization Pathways in RNA
por: Chandorkar, Shreya, et al.
Publicado: (2021)

Alchemical Free-Energy Calculations of Watson–Crick and Hoogsteen Base Pairing Interconversion in DNA
por: Geronimo, Inacrist, et al.
Publicado: (2022)

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry
por: Betz, Karin, et al.
Publicado: (2012)

Comparable Stability of Hoogsteen and Watson–Crick Base Pairs in Ionic Liquid Choline Dihydrogen Phosphate
por: Tateishi-Karimata, Hisae, et al.
Publicado: (2014)

(1)H R(1ρ) relaxation dispersion experiments in aromatic side chains
por: Dreydoppel, Matthias, et al.
Publicado: (2021)

Comprehensive thermodynamic analysis of 3′ double-nucleotide overhangs neighboring Watson–Crick terminal base pairs
por: O'Toole, Amanda S., et al.
Publicado: (2006)

Characterization of the Trans Watson-Crick GU Base Pair Located in the Catalytic Core of the Antigenomic HDV Ribozyme
por: Lévesque, Dominique, et al.
Publicado: (2012)

Silver (I) as DNA glue: Ag(+)-mediated guanine pairing revealed by removing Watson-Crick constraints
por: Swasey, Steven M., et al.
Publicado: (2015)

Validation of the nearest-neighbor model for Watson–Crick self-complementary DNA duplexes in molecular crowding condition
por: Ghosh, Saptarshi, et al.
Publicado: (2019)

Context-sensitivity of isosteric substitutions of non-Watson–Crick basepairs in recurrent RNA 3D motifs
por: Khisamutdinov, Emil F, et al.
Publicado: (2021)

Watson-Crick Base-Pairing Requirements for ssDNA Recognition and Processing in Replication-Initiating HUH Endonucleases
por: Smiley, Adam T., et al.
Publicado: (2022)

DNA mismatches reveal conformational penalties in protein-DNA recognition
por: Afek, Ariel, et al.
Publicado: (2020)

Magnetic Resonance Water Proton Relaxation in Protein Solutions and Tissue: T(1ρ) Dispersion Characterization
por: Chen, Enn-Ling, et al.
Publicado: (2010)

Higher order structural effects stabilizing the reverse Watson–Crick Guanine-Cytosine base pair in functional RNAs
por: Chawla, Mohit, et al.
Publicado: (2014)

Free energy landscape and transition pathways from Watson–Crick to Hoogsteen base pairing in free duplex DNA
por: Yang, Changwon, et al.
Publicado: (2015)

Selective prebiotic conversion of pyrimidine and purine anhydronucleosides into Watson-Crick base-pairing arabino-furanosyl nucleosides in water
por: Roberts, Samuel J., et al.
Publicado: (2018)

Molecular crowding induces primer extension by RNA polymerase through base stacking beyond Watson–Crick rules
por: Takahashi, Shuntaro, et al.
Publicado: (2020)

Nearest neighbor parameters for Watson–Crick complementary heteroduplexes formed between 2′-O-methyl RNA and RNA oligonucleotides
por: Kierzek, Elzbieta, et al.
Publicado: (2006)

Rapid and accurate determination of atomistic RNA dynamic ensemble models using NMR and structure prediction
por: Shi, Honglue, et al.
Publicado: (2020)

Intermolecular ‘cross-torque’: the N(4)-cytosine propargyl residue is rotated to the ‘CH’-edge as a result of Watson–Crick interaction
por: Domingo, Olwen, et al.
Publicado: (2015)

Watson‐Crick Base Pairing of N‐Methoxy‐1,3‐Oxazinane (MOANA) Nucleoside Analogues within Double‐Helical DNA
por: Afari, Mark N. K., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ut4gmrln6it2lrk85bf57hi5ch