Cargando…
Comprehensive histone epigenetics: A mass spectrometry based screening assay to measure epigenetic toxicity
• There is a growing interest in epigenetic modifications, and more specifically in histone post-translational modifications (hPTMs). • We describe an MS-based workflow that is capable of tracking all possible hPTMs in an untargeted approach that makes use of human cells. • Improving the workflow an...
Autores principales: | Verhelst, Sigrid, De Clerck, Laura, Willems, Sander, Van Puyvelde, Bart, Daled, Simon, Deforce, Dieter, Dhaenens, Maarten |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508989/ https://www.ncbi.nlm.nih.gov/pubmed/32995308 http://dx.doi.org/10.1016/j.mex.2020.101055 |
Ejemplares similares
-
A large scale mass spectrometry-based histone screening for assessing epigenetic developmental toxicity
por: Verhelst, Sigrid, et al.
Publicado: (2022) -
Histone Sample Preparation for Bottom-Up Mass Spectrometry: A Roadmap to Informed Decisions
por: Daled, Simon, et al.
Publicado: (2021) -
An interactive mass spectrometry atlas of histone posttranslational modifications in T-cell acute leukemia
por: Provez, Lien, et al.
Publicado: (2022) -
Tackling aspecific side reactions during histone propionylation: The promise of reversing overpropionylation
por: Meert, Paulien, et al.
Publicado: (2016) -
Micro‐Topographies Induce Epigenetic Reprogramming and Quiescence in Human Mesenchymal Stem Cells
por: Vermeulen, Steven, et al.
Publicado: (2022)