Cargando…
A rare maternal gastrointestinal stromal tumor found in the second trimester of pregnancy: A case report
Gastrointestinal stromal tumors are rare, and in pregnancy they are extremely rare. We present a case of a maternal gastrointestinal stromal tumor found in the second trimester of pregnancy. A 29-year-old woman, gravida 1 para 0, complained of bloody vomiting at 14 weeks of gestation. She had no sig...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508991/ https://www.ncbi.nlm.nih.gov/pubmed/32995306 http://dx.doi.org/10.1016/j.crwh.2020.e00251 |
_version_ | 1783585509519392768 |
---|---|
author | Tanaka, Naoko Tamada, Shoko Ueno, Naoko Ishida, Makoto Kodama, Junichi Kubota, Tetsushi |
author_facet | Tanaka, Naoko Tamada, Shoko Ueno, Naoko Ishida, Makoto Kodama, Junichi Kubota, Tetsushi |
author_sort | Tanaka, Naoko |
collection | PubMed |
description | Gastrointestinal stromal tumors are rare, and in pregnancy they are extremely rare. We present a case of a maternal gastrointestinal stromal tumor found in the second trimester of pregnancy. A 29-year-old woman, gravida 1 para 0, complained of bloody vomiting at 14 weeks of gestation. She had no significant medical history. We performed plain computed tomography and upper gastrointestinal endoscopy. Precise examination revealed a large mass in the stomach and an exposed blood vessel on the surface. An exposed blood vessel can be harmful for mother and fetus as it might rupture during the pregnancy. We performed a distal gastrectomy at 16 weeks of gestation. Histology confirmed a localized gastrointestinal stromal tumor with a high risk of recurrence, and adjuvant imatinib was recommended. The patient elected to delay adjuvant imatinib until after delivery. The postoperative and antenatal course was favorable, and the patient was followed up by ultrasound every 2 months after the operation. After she gave birth at 40 weeks of gestation, she started adjuvant imatinib 400 mg/day. There was no evidence of recurrence 1 year after surgery. There are no guidelines for the management of gastrointestinal stromal tumors in pregnancy. Given the treatment challenges, we believe that pregnant patients should be managed by a multidisciplinary team with expertise in gastrointestinal tumors and fetal-maternal medicine. |
format | Online Article Text |
id | pubmed-7508991 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-75089912020-09-28 A rare maternal gastrointestinal stromal tumor found in the second trimester of pregnancy: A case report Tanaka, Naoko Tamada, Shoko Ueno, Naoko Ishida, Makoto Kodama, Junichi Kubota, Tetsushi Case Rep Womens Health Article Gastrointestinal stromal tumors are rare, and in pregnancy they are extremely rare. We present a case of a maternal gastrointestinal stromal tumor found in the second trimester of pregnancy. A 29-year-old woman, gravida 1 para 0, complained of bloody vomiting at 14 weeks of gestation. She had no significant medical history. We performed plain computed tomography and upper gastrointestinal endoscopy. Precise examination revealed a large mass in the stomach and an exposed blood vessel on the surface. An exposed blood vessel can be harmful for mother and fetus as it might rupture during the pregnancy. We performed a distal gastrectomy at 16 weeks of gestation. Histology confirmed a localized gastrointestinal stromal tumor with a high risk of recurrence, and adjuvant imatinib was recommended. The patient elected to delay adjuvant imatinib until after delivery. The postoperative and antenatal course was favorable, and the patient was followed up by ultrasound every 2 months after the operation. After she gave birth at 40 weeks of gestation, she started adjuvant imatinib 400 mg/day. There was no evidence of recurrence 1 year after surgery. There are no guidelines for the management of gastrointestinal stromal tumors in pregnancy. Given the treatment challenges, we believe that pregnant patients should be managed by a multidisciplinary team with expertise in gastrointestinal tumors and fetal-maternal medicine. Elsevier 2020-08-22 /pmc/articles/PMC7508991/ /pubmed/32995306 http://dx.doi.org/10.1016/j.crwh.2020.e00251 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Tanaka, Naoko Tamada, Shoko Ueno, Naoko Ishida, Makoto Kodama, Junichi Kubota, Tetsushi A rare maternal gastrointestinal stromal tumor found in the second trimester of pregnancy: A case report |
title | A rare maternal gastrointestinal stromal tumor found in the second trimester of pregnancy: A case report |
title_full | A rare maternal gastrointestinal stromal tumor found in the second trimester of pregnancy: A case report |
title_fullStr | A rare maternal gastrointestinal stromal tumor found in the second trimester of pregnancy: A case report |
title_full_unstemmed | A rare maternal gastrointestinal stromal tumor found in the second trimester of pregnancy: A case report |
title_short | A rare maternal gastrointestinal stromal tumor found in the second trimester of pregnancy: A case report |
title_sort | rare maternal gastrointestinal stromal tumor found in the second trimester of pregnancy: a case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508991/ https://www.ncbi.nlm.nih.gov/pubmed/32995306 http://dx.doi.org/10.1016/j.crwh.2020.e00251 |
work_keys_str_mv | AT tanakanaoko ararematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport AT tamadashoko ararematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport AT uenonaoko ararematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport AT ishidamakoto ararematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport AT kodamajunichi ararematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport AT kubotatetsushi ararematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport AT tanakanaoko rarematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport AT tamadashoko rarematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport AT uenonaoko rarematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport AT ishidamakoto rarematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport AT kodamajunichi rarematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport AT kubotatetsushi rarematernalgastrointestinalstromaltumorfoundinthesecondtrimesterofpregnancyacasereport |