Enhancing the Mitochondrial Uptake of Phosphonium Cations by Carboxylic Acid Incorporation

There is considerable interest in developing drugs and probes targeted to mitochondria in order to understand and treat the many pathologies associated with mitochondrial dysfunction. The large membrane potential, negative inside, across the mitochondrial inner membrane enables delivery of molecules...

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Detalles Bibliográficos
Autores principales: Pala, Laura, Senn, Hans M., Caldwell, Stuart T., Prime, Tracy A., Warrington, Stefan, Bright, Thomas P., Prag, Hiran A., Wilson, Claire, Murphy, Michael P., Hartley, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509049/
https://www.ncbi.nlm.nih.gov/pubmed/33033715
http://dx.doi.org/10.3389/fchem.2020.00783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509049/
https://www.ncbi.nlm.nih.gov/pubmed/33033715
http://dx.doi.org/10.3389/fchem.2020.00783

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