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Enhancing the Mitochondrial Uptake of Phosphonium Cations by Carboxylic Acid Incorporation
There is considerable interest in developing drugs and probes targeted to mitochondria in order to understand and treat the many pathologies associated with mitochondrial dysfunction. The large membrane potential, negative inside, across the mitochondrial inner membrane enables delivery of molecules...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509049/ https://www.ncbi.nlm.nih.gov/pubmed/33033715 http://dx.doi.org/10.3389/fchem.2020.00783 |