Infection by the Protozoan Parasite Toxoplasma gondii Inhibits Host MNK1/2-eIF4E Axis to Promote Its Survival

The obligate intracellular parasite Toxoplasma gondii reprograms host gene expression through multiple mechanisms that promote infection, including the up-regulation of mTOR-dependent host mRNA translation. In addition to the mTOR-4E-BP1/2 axis, MAPK-interacting kinases 1 and 2 (MNK1/2) control the...

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Detalles Bibliográficos
Autores principales: Leroux, Louis-Philippe, Chaparro, Visnu, Jaramillo, Maritza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509071/
https://www.ncbi.nlm.nih.gov/pubmed/33014898
http://dx.doi.org/10.3389/fcimb.2020.00488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509071/
https://www.ncbi.nlm.nih.gov/pubmed/33014898
http://dx.doi.org/10.3389/fcimb.2020.00488

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