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Fatty Acid Synthesis Is Indispensable for Survival of Human Pluripotent Stem Cells

The role of lipid metabolism in human pluripotent stem cells (hPSCs) is poorly understood. We have used large-scale targeted proteomics to demonstrate that undifferentiated hPSCs express different fatty acid (FA) biosynthesis-related enzymes, including ATP citrate lyase and FA synthase (FASN), than...

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Detalles Bibliográficos
Autores principales:	Tanosaki, Sho, Tohyama, Shugo, Fujita, Jun, Someya, Shota, Hishiki, Takako, Matsuura, Tomomi, Nakanishi, Hiroki, Ohto-Nakanishi, Takayo, Akiyama, Tomohiko, Morita, Yuika, Kishino, Yoshikazu, Okada, Marina, Tani, Hidenori, Soma, Yusuke, Nakajima, Kazuaki, Kanazawa, Hideaki, Sugimoto, Masahiro, Ko, Minoru S.H., Suematsu, Makoto, Fukuda, Keiichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509212/ https://www.ncbi.nlm.nih.gov/pubmed/33083764 http://dx.doi.org/10.1016/j.isci.2020.101535

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