First Responders Shape a Prompt and Sharp NF-κB-Mediated Transcriptional Response to TNF-α

Nuclear factor (NF)-κB controls the transcriptional response to inflammatory signals by translocating into the nucleus, but we lack a single-cell characterization of the resulting transcription dynamics. Here we show that upon tumor necrosis factor (TNF)-α transcription of NF-κB target genes is hete...

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Detalles Bibliográficos
Autores principales: Zambrano, Samuel, Loffreda, Alessia, Carelli, Elena, Stefanelli, Giacomo, Colombo, Federica, Bertrand, Edouard, Tacchetti, Carlo, Agresti, Alessandra, Bianchi, Marco E., Molina, Nacho, Mazza, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509218/
https://www.ncbi.nlm.nih.gov/pubmed/33083759
http://dx.doi.org/10.1016/j.isci.2020.101529

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