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Cervical Dystonia Refractory to Botulinum Toxin Responding to Radiofrequency Ablation: A Case Report

A 62-year-old male diagnosed with cervical dystonia (CD) and chronic right-sided neck pain presented to the Pain Clinic after his pain and CD symptoms failed to resolve with botulinum toxin therapy. During clinical examination, right C3-C4 and C4-C5 facet arthropathy was suspected. After two sets of...

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Autores principales: Dey, Saugat, Ghosh, Sayantani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509331/
https://www.ncbi.nlm.nih.gov/pubmed/32982394
http://dx.doi.org/10.2147/JPR.S271945
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author Dey, Saugat
Ghosh, Sayantani
author_facet Dey, Saugat
Ghosh, Sayantani
author_sort Dey, Saugat
collection PubMed
description A 62-year-old male diagnosed with cervical dystonia (CD) and chronic right-sided neck pain presented to the Pain Clinic after his pain and CD symptoms failed to resolve with botulinum toxin therapy. During clinical examination, right C3-C4 and C4-C5 facet arthropathy was suspected. After two sets of diagnostic right cervical, C3, C4, and C5 medial branch blocks provided >80% pain relief; cervical radiofrequency ablation (CRFA) was performed. Post CRFA, the patient was followed for 12 months. Till the last follow-up, he was not only experiencing 90% pain relief, but also had significant improvement in his CD symptoms to the point that he no longer needed botulinum toxin and other CD-related therapy. This report suggests that large-scale research is required to postulate whether CD patients, whose symptoms are refractory to botulinum toxin, should be routinely screened for cervical facet arthropathy. This is the first reported case of improvement in CD symptoms with CRFA. This effect could be explained by the fact that certain deep cervical muscles, which are affected in CD, are innervated by medial branch nerves.
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spelling pubmed-75093312020-09-24 Cervical Dystonia Refractory to Botulinum Toxin Responding to Radiofrequency Ablation: A Case Report Dey, Saugat Ghosh, Sayantani J Pain Res Case Report A 62-year-old male diagnosed with cervical dystonia (CD) and chronic right-sided neck pain presented to the Pain Clinic after his pain and CD symptoms failed to resolve with botulinum toxin therapy. During clinical examination, right C3-C4 and C4-C5 facet arthropathy was suspected. After two sets of diagnostic right cervical, C3, C4, and C5 medial branch blocks provided >80% pain relief; cervical radiofrequency ablation (CRFA) was performed. Post CRFA, the patient was followed for 12 months. Till the last follow-up, he was not only experiencing 90% pain relief, but also had significant improvement in his CD symptoms to the point that he no longer needed botulinum toxin and other CD-related therapy. This report suggests that large-scale research is required to postulate whether CD patients, whose symptoms are refractory to botulinum toxin, should be routinely screened for cervical facet arthropathy. This is the first reported case of improvement in CD symptoms with CRFA. This effect could be explained by the fact that certain deep cervical muscles, which are affected in CD, are innervated by medial branch nerves. Dove 2020-09-18 /pmc/articles/PMC7509331/ /pubmed/32982394 http://dx.doi.org/10.2147/JPR.S271945 Text en © 2020 Dey and Ghosh. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Dey, Saugat
Ghosh, Sayantani
Cervical Dystonia Refractory to Botulinum Toxin Responding to Radiofrequency Ablation: A Case Report
title Cervical Dystonia Refractory to Botulinum Toxin Responding to Radiofrequency Ablation: A Case Report
title_full Cervical Dystonia Refractory to Botulinum Toxin Responding to Radiofrequency Ablation: A Case Report
title_fullStr Cervical Dystonia Refractory to Botulinum Toxin Responding to Radiofrequency Ablation: A Case Report
title_full_unstemmed Cervical Dystonia Refractory to Botulinum Toxin Responding to Radiofrequency Ablation: A Case Report
title_short Cervical Dystonia Refractory to Botulinum Toxin Responding to Radiofrequency Ablation: A Case Report
title_sort cervical dystonia refractory to botulinum toxin responding to radiofrequency ablation: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509331/
https://www.ncbi.nlm.nih.gov/pubmed/32982394
http://dx.doi.org/10.2147/JPR.S271945
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