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RPL21 siRNA Blocks Proliferation in Pancreatic Cancer Cells by Inhibiting DNA Replication and Inducing G1 Arrest and Apoptosis

BACKGROUND: Our previous study showed that the ribosomal protein L21 (RPL21) may play an important role in the development and survival of pancreatic cancer. In this article, RNA interference (RNAi) experiments were performed with RPL21-specific small interfering RNA (siRNA) to elucidate the mechani...

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Detalles Bibliográficos
Autores principales: Li, Chaodong, Ge, Mei, Chen, Daijie, Sun, Tao, Jiang, Hua, Xie, Yueqing, Lu, Huili, Zhang, Baohong, Han, Lei, Chen, Junsheng, Zhu, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509406/
https://www.ncbi.nlm.nih.gov/pubmed/33014855
http://dx.doi.org/10.3389/fonc.2020.01730