Tethering of Telomeres to the Nuclear Envelope Is Mediated by SUN1-MAJIN and Possibly Promoted by SPDYA-CDK2 During Meiosis

During meiosis, telomeres attach to the nuclear envelope (NE) to promote homologous chromosome moving, pairing, synapsis, and recombination. The telomere-NE attachment is mediated by SUN1, TERB1-TERB2-MAJIN (TTM complex), and TRF1. The interaction of the TTM complex with shelterin is mediated by TER...

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Detalles Bibliográficos
Autores principales: Wang, Guishuan, Wu, Xiaolong, Zhou, Liwei, Gao, Sheng, Yun, Damin, Liang, Ajuan, Sun, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509418/
https://www.ncbi.nlm.nih.gov/pubmed/33015044
http://dx.doi.org/10.3389/fcell.2020.00845

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