Cargando…

A Computational Model of the Cholinergic Modulation of CA1 Pyramidal Cell Activity

Dysfunction in cholinergic modulation has been linked to a variety of cognitive disorders including Alzheimer's disease. The important role of this neurotransmitter has been explored in a variety of experiments, yet many questions remain unanswered about the contribution of cholinergic modulati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mergenthal, Adam, Bouteiller, Jean-Marie C., Yu, Gene J., Berger, Theodore W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509450/ https://www.ncbi.nlm.nih.gov/pubmed/33013341 http://dx.doi.org/10.3389/fncom.2020.00075

Ejemplares similares

A Glutamatergic Spine Model to Enable Multi-Scale Modeling of Nonlinear Calcium Dynamics
por: Hu, Eric, et al.
Publicado: (2018)

Topographic Organization of Correlation Along the Longitudinal and Transverse Axes in Rat Hippocampal CA3 Due to Excitatory Afferents
por: Yu, Gene J., et al.
Publicado: (2020)

ROOTS: An Algorithm to Generate Biologically Realistic Cortical Axons and an Application to Electroceutical Modeling
por: Bingham, Clayton S., et al.
Publicado: (2020)

Bridging Hierarchies in Multi-Scale Models of Neural Systems: Look-Up Tables Enable Computationally Efficient Simulations of Non-linear Synaptic Dynamics
por: Pham, Duy-Tan J., et al.
Publicado: (2021)

Cholinergic modulation shifts the response of CA1 pyramidal cells to depolarizing ramps via TRPM4 channels with potential implications for place field firing
por: Combe, Crescent L, et al.
Publicado: (2023)

Confocal Analysis of Cholinergic and Dopaminergic Inputs onto Pyramidal Cells in the Prefrontal Cortex of Rodents
por: Zhang, Zi-Wei, et al.
Publicado: (2010)

Cholinergic modulation of cognitive processing: insights drawn from computational models
por: Newman, Ehren L., et al.
Publicado: (2012)

Pyramidal tract neurons drive amplification of excitatory inputs to striatum through cholinergic interneurons
por: Morgenstern, Nicolás A., et al.
Publicado: (2022)

A Computational Model to Investigate Astrocytic Glutamate Uptake Influence on Synaptic Transmission and Neuronal Spiking
por: Allam, Sushmita L., et al.
Publicado: (2012)

Volterra representation enables modeling of complex synaptic nonlinear dynamics in large-scale simulations
por: Hu, Eric Y., et al.
Publicado: (2015)

Basal Forebrain Cholinergic Activity Modulates Isoflurane and Propofol Anesthesia
por: Luo, Tian-Yuan, et al.
Publicado: (2020)

Alpha7 Nicotinic Acetylcholine Receptors Play a Predominant Role in the Cholinergic Potentiation of N-Methyl-D-Aspartate Evoked Firing Responses of Hippocampal CA1 Pyramidal Cells
por: Bali, Zsolt K., et al.
Publicado: (2017)

CA1 pyramidal cell diversity is rooted in the time of neurogenesis
por: Cavalieri, Davide, et al.
Publicado: (2021)

Modulation of BK channels contributes to activity-dependent increase of excitability through MTORC1 activity in CA1 pyramidal cells of mouse hippocampus
por: Springer, Steven J., et al.
Publicado: (2015)

Distinct dendritic Ca(2+) spike forms produce opposing input-output transformations in rat CA3 pyramidal cells
por: Magó, Ádám, et al.
Publicado: (2021)

Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels
por: Kratzer, Stephan, et al.
Publicado: (2013)

Cholinergic modulation of hippocampal network function
por: Teles-Grilo Ruivo, Leonor M., et al.
Publicado: (2013)

The kinetics of multibranch integration on the dendritic arbor of CA1 pyramidal neurons
por: Yang, Sunggu, et al.
Publicado: (2014)

Analysis of Age-Dependent Alterations in Excitability Properties of CA1 Pyramidal Neurons in an APPPS1 Model of Alzheimer’s Disease
por: Vitale, Paola, et al.
Publicado: (2021)

Insulin Modulates Neural Activity of Pyramidal Neurons in the Anterior Piriform Cortex
por: Zhou, Yang, et al.
Publicado: (2017)

Admittance Method for Estimating Local Field Potentials Generated in a Multi-Scale Neuron Model of the Hippocampus
por: Bingham, Clayton S., et al.
Publicado: (2020)

Data-Driven Modeling of Cholinergic Modulation of Neural Microcircuits: Bridging Neurons, Synapses and Network Activity
por: Ramaswamy, Srikanth, et al.
Publicado: (2018)

Reproducing and quantitatively validating a biologically-constrained point-neuron model of CA1 pyramidal cells
por: Appukuttan, Shailesh, et al.
Publicado: (2022)

Cholinergic modulation of hippocampal calcium activity across the sleep-wake cycle
por: Zhou, Heng, et al.
Publicado: (2019)

Optogenetic inhibition-mediated activity-dependent modification of CA1 pyramidal-interneuron connections during behavior
por: Gridchyn, Igor, et al.
Publicado: (2020)

Extreme Neuroplasticity of Hippocampal CA1 Pyramidal Neurons in Hibernating Mammalian Species
por: Horowitz, John M., et al.
Publicado: (2019)

Heterogeneous CaMKII-Dependent Synaptic Compensations in CA1 Pyramidal Neurons From Acute Hippocampal Slices
por: Vergara, Pablo, et al.
Publicado: (2022)

A critical role for CaMKII in behavioral timescale synaptic plasticity in hippocampal CA1 pyramidal neurons
por: Xiao, Kuo, et al.
Publicado: (2023)

Orexin Receptor Activation Generates Gamma Band Input to Cholinergic and Serotonergic Arousal System Neurons and Drives an Intrinsic Ca(2+)-Dependent Resonance in LDT and PPT Cholinergic Neurons
por: Ishibashi, Masaru, et al.
Publicado: (2015)

Opposing Cholinergic and Serotonergic Modulation of Layer 6 in Prefrontal Cortex
por: Sparks, Daniel W., et al.
Publicado: (2018)

Three axonal projection routes of individual pyramidal cells in the ventral CA1 hippocampus
por: Arszovszki, Antónia, et al.
Publicado: (2014)

Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice
por: Tamagnini, Francesco, et al.
Publicado: (2015)

Coexistence of Multiple Types of Synaptic Plasticity in Individual Hippocampal CA1 Pyramidal Neurons
por: Edelmann, Elke, et al.
Publicado: (2017)

Metabolic Cost of Dendritic Ca(2+) Action Potentials in Layer 5 Pyramidal Neurons
por: Yi, Guosheng, et al.
Publicado: (2019)

Dopamine Modulates Spike Timing-Dependent Plasticity and Action Potential Properties in CA1 Pyramidal Neurons of Acute Rat Hippocampal Slices
por: Edelmann, Elke, et al.
Publicado: (2011)

Simulation of cholinergic and noradrenergic modulation of behavior in uncertain environments
por: Avery, Michael C., et al.
Publicado: (2012)

Noradrenergic and cholinergic modulation of olfactory bulb sensory processing
por: Devore, Sasha, et al.
Publicado: (2012)

Interactions between Inhibitory Interneurons and Excitatory Associational Circuitry in Determining Spatio-Temporal Dynamics of Hippocampal Dentate Granule Cells: A Large-Scale Computational Study
por: Hendrickson, Phillip J., et al.
Publicado: (2015)

Plasticity-dependent, full detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses
por: Vyleta, Nicholas P, et al.
Publicado: (2016)

Local Optogenetic Induction of Fast (20–40 Hz) Pyramidal-Interneuron Network Oscillations in the In Vitro and In Vivo CA1 Hippocampus: Modulation by CRF and Enforcement of Perirhinal Theta Activity
por: Dine, Julien, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_fjic4u067ugd716ncn4q10vos0