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To What Extent Do Fluorophores Bias the Biological Activity of Peptides? A Practical Approach Using Membrane-Active Peptides as Models

The characterization of biologically active peptides relies heavily on the study of their efficacy, toxicity, mechanism of action, cellular uptake, or intracellular location, using both in vitro and in vivo studies. These studies frequently depend on the use of fluorescence-based techniques. Since m...

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Detalles Bibliográficos
Autores principales: Cavaco, Marco, Pérez-Peinado, Clara, Valle, Javier, Silva, Rúben D. M., Correia, João D. G., Andreu, David, Castanho, Miguel A. R. B., Neves, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509492/
https://www.ncbi.nlm.nih.gov/pubmed/33015016
http://dx.doi.org/10.3389/fbioe.2020.552035