The anti-B7-H4 checkpoint synergizes trastuzumab treatment to promote phagocytosis and eradicate breast cancer

Trastuzumab is a humanized mAb used to treat HER2-overexpressing breast cancer; however its mechanisms remain to be fully elucidated. Previous studies suggest a role for immunity in mediating trastuzumab-specific antitumor effects. This study evaluated the role(s) of trastuzumab and other antibodies...

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Detalles Bibliográficos
Autores principales: Hu, Xiaochen, Liu, Yiwen, Zhang, Xiusen, Kong, Dejiu, Kong, Jinyu, Zhao, Di, Guo, Yibo, Sun, Lingyun, Chu, Luoyi, Liu, Shupei, Hou, Xurong, Ren, Feng, Zhao, Ying, Lu, Chengbiao, Zhai, Desheng, Yuan, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509589/
https://www.ncbi.nlm.nih.gov/pubmed/32966956
http://dx.doi.org/10.1016/j.neo.2020.08.007

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