Cargando…

Machine Learning‐Assisted Evaluation of Circulating DNA Quantitative Analysis for Cancer Screening

While the utility of circulating cell‐free DNA (cfDNA) in cancer screening and early detection have recently been investigated by testing genetic and epigenetic alterations, here, an original approach by examining cfDNA quantitative and structural features is developed. First, the potential of cfDNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanos, Rita, Tosato, Guillaume, Otandault, Amaelle, Al Amir Dache, Zahra, Pique Lasorsa, Laurence, Tousch, Geoffroy, El Messaoudi, Safia, Meddeb, Romain, Diab Assaf, Mona, Ychou, Marc, Du Manoir, Stanislas, Pezet, Denis, Gagnière, Johan, Colombo, Pierre‐Emmanuel, Jacot, William, Assénat, Eric, Dupuy, Marie, Adenis, Antoine, Mazard, Thibault, Mollevi, Caroline, Sayagués, José María, Colinge, Jacques, Thierry, Alain R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509651/ https://www.ncbi.nlm.nih.gov/pubmed/32999827 http://dx.doi.org/10.1002/advs.202000486

Ejemplares similares

Quantifying circulating cell-free DNA in humans
por: Meddeb, Romain, et al.
Publicado: (2019)

Sequential first-line treatment with nab-paclitaxel/gemcitabine and FOLFIRINOX in metastatic pancreatic adenocarcinoma: GABRINOX phase Ib-II controlled clinical trial
por: Assenat, E., et al.
Publicado: (2021)

FOLFIRINOX-R study design: a phase I/II trial of FOLFIRINOX plus regorafenib as first line therapy in patients with unresectable RAS-mutated metastatic colorectal cancer
por: Adenis, Antoine, et al.
Publicado: (2021)

Hypoxia differently modulates the release of mitochondrial and nuclear DNA
por: Otandault, Amaelle, et al.
Publicado: (2020)

Inhibition of DDR1‐BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer
por: Jeitany, Maya, et al.
Publicado: (2018)

Advocacy for colorectal cancer screening and awareness in people with intellectual disability
por: Satgé, Daniel, et al.
Publicado: (2023)

Association of neutrophil extracellular traps with the production of circulating DNA in patients with colorectal cancer
por: Pastor, Brice, et al.
Publicado: (2022)

Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse
por: du Manoir, Stanislas, et al.
Publicado: (2013)

Circulating nuclear DNA structural features, origins, and complete size profile revealed by fragmentomics
por: Sanchez, Cynthia, et al.
Publicado: (2021)

Stereotactic MR-Guided Radiotherapy for Liver Metastases: First Results of the Montpellier Prospective Registry Study
por: Bordeau, Karl, et al.
Publicado: (2023)

Reverse transcription-quantitative polymerase chain reaction: description of a RIN-based algorithm for accurate data normalization
por: Ho-Pun-Cheung, Alexandre, et al.
Publicado: (2009)

Sorafenib and irinotecan (NEXIRI) as second- or later-line treatment for patients with metastatic colorectal cancer and KRAS-mutated tumours: a multicentre Phase I/II trial
por: Samalin, E, et al.
Publicado: (2014)

Mechanical signatures of human colon cancers
por: Lopez-Crapez, Evelyne, et al.
Publicado: (2022)

The landscape of cancer-associated fibroblasts in colorectal cancer liver metastases
por: Giguelay, Ambre, et al.
Publicado: (2022)

Resection of pancreatic ductal adenocarcinoma with synchronous distant metastasis: is it worthwhile?
por: Buc, Emmanuel, et al.
Publicado: (2014)

An original technique of venous autoplasty after duodenopancreatectomy for tumors involving the infrarenal inferior vena cava
por: Le Roy, Bertrand, et al.
Publicado: (2017)

A straightforward method to quantify circulating mRNAs as biomarkers of colorectal cancer
por: Grosgeorges, Marie, et al.
Publicado: (2023)

Quantification of HER Expression and Dimerization in Patients’ Tumor Samples Using Time-Resolved Förster Resonance Energy Transfer
por: Ho-Pun-Cheung, Alexandre, et al.
Publicado: (2012)

Selective treatment pressure in colon cancer drives the molecular profile of resistant circulating tumor cell clones
por: Cayrefourcq, Laure, et al.
Publicado: (2021)

Specific Extracellular Matrix Remodeling Signature of Colon Hepatic Metastases
por: Del Rio, Maguy, et al.
Publicado: (2013)

Clinical Relevance of Viable Circulating Tumor Cells in Patients with Metastatic Colorectal Cancer: The COLOSPOT Prospective Study
por: Mazard, Thibault, et al.
Publicado: (2021)

Dual targeting of HER1/EGFR and HER2 with cetuximab and trastuzumab in patients with metastatic pancreatic cancer after gemcitabine failure: results of the “THERAPY”phase 1-2 trial
por: Assenat, Eric, et al.
Publicado: (2015)

The oncogenic and druggable hPG80 (Progastrin) is overexpressed in multiple cancers and detected in the blood of patients
por: You, Benoit, et al.
Publicado: (2019)

A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment
por: Alcaraz, Lindsay B, et al.
Publicado: (2021)

CXCR2 Levels Correlate with Immune Infiltration and a Better Prognosis of Triple-Negative Breast Cancers
por: Boissière-Michot, Florence, et al.
Publicado: (2021)

The quest for the optimal biomarker: is extending the spectrum of targeted PIK3CA mutations in breast cancer carcinoma worthwhile?
por: Quesada, Stanislas, et al.
Publicado: (2023)

Does intraoperative closed-suction drainage influence the rate of pancreatic fistula after pancreaticoduodenectomy?
por: Aumont, Ophélie, et al.
Publicado: (2017)

Association of COVID-19 Lockdown With the Tumor Burden in Patients With Newly Diagnosed Metastatic Colorectal Cancer
por: Thierry, Alain R., et al.
Publicado: (2021)

Comparison of the structures and topologies of plasma extracted circulating nuclear and mitochondrial cell-free DNA
por: Pisareva, Ekaterina, et al.
Publicado: (2023)

Lean body mass as an independent determinant of dose‐limiting toxicity and neuropathy in patients with colon cancer treated with FOLFOX regimens
por: Ali, Raafi, et al.
Publicado: (2016)

Autologous cell lines from circulating colon cancer cells captured from sequential liquid biopsies as model to study therapy-driven tumor changes
por: Soler, Alexandra, et al.
Publicado: (2018)

Modulating PKCα Activity to Target Wnt/β-Catenin Signaling in Colon Cancer
por: Dupasquier, Sébastien, et al.
Publicado: (2019)

Stereotactic MR-Guided Adaptive Radiotherapy for Pancreatic Tumors: Updated Results of the Montpellier Prospective Registry Study
por: Bordeau, Karl, et al.
Publicado: (2022)

Signalling with retinoids in the human lung: validation of new tools for the expression study of retinoid receptors
por: Poulain, Stéphane, et al.
Publicado: (2009)

The p53 isoform delta133p53ß regulates cancer cell apoptosis in a RhoB-dependent manner
por: Arsic, Nikola, et al.
Publicado: (2017)

A human RNA polymerase II subunit is encoded by a recently generated multigene family
por: Grandemange, Sylvie, et al.
Publicado: (2001)

Prognostic value of a combination of innovative factors (gut microbiota, sarcopenia, obesity, metabolic syndrome) to predict surgical/oncologic outcomes following surgery for sporadic colorectal cancer: a prospective cohort study protocol (METABIOTE)
por: Veziant, Julie, et al.
Publicado: (2020)

Stereotactic MR-Guided Radiotherapy for Pancreatic Tumors: Dosimetric Benefit of Adaptation and First Clinical Results in a Prospective Registry Study
por: Michalet, Morgan, et al.
Publicado: (2022)

Inferring ligand-receptor cellular networks from bulk and spatial transcriptomic datasets with BulkSignalR
por: Villemin, Jean-Philippe, et al.
Publicado: (2023)

Correction: The p53 isoform delta133p53ß regulates cancer cell apoptosis in a RhoB-dependent manner
por: Arsic, Nikola, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sp4braf47d7b3t0rrqoaogori5