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Sleep Timing in Patients with Precocious and Delayed Pubertal Development

Previous studies have reported a shift in the timing of sleep during adolescence toward a later time. To date, it is unclear whether hormonal changes during puberty might contribute to this change in sleeping behavior. We systematically assessed pubertal development and sleep timing in a cross-secti...

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Autores principales: Jessen, Elena, Vetter, Celine, Roenneberg, Till, Liesenkötter, Klaus-Peter, Werner, Helene, Jenni, Oskar G., Lankes, Erwin, Blankenstein, Oliver, Neumann, Uta, Köhler, Birgit, Wiegand, Susanna, Krude, Heiko, Kühnen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509672/
https://www.ncbi.nlm.nih.gov/pubmed/33089160
http://dx.doi.org/10.3390/clockssleep1010013
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author Jessen, Elena
Vetter, Celine
Roenneberg, Till
Liesenkötter, Klaus-Peter
Werner, Helene
Jenni, Oskar G.
Lankes, Erwin
Blankenstein, Oliver
Neumann, Uta
Köhler, Birgit
Wiegand, Susanna
Krude, Heiko
Kühnen, Peter
author_facet Jessen, Elena
Vetter, Celine
Roenneberg, Till
Liesenkötter, Klaus-Peter
Werner, Helene
Jenni, Oskar G.
Lankes, Erwin
Blankenstein, Oliver
Neumann, Uta
Köhler, Birgit
Wiegand, Susanna
Krude, Heiko
Kühnen, Peter
author_sort Jessen, Elena
collection PubMed
description Previous studies have reported a shift in the timing of sleep during adolescence toward a later time. To date, it is unclear whether hormonal changes during puberty might contribute to this change in sleeping behavior. We systematically assessed pubertal development and sleep timing in a cross-sectional case-control study in girls with precocious (n = 42) and boys with delayed pubertal development (n = 19). We used the Munich ChronoType Questionnaire and the Children’s ChronoType Questionnaire to assess sleep timing in patients and age- and sex-matched controls (n = 309) and used the midpoint of sleep on free days, corrected for potential sleep debt accumulated during the school week, as a marker for sleep timing. Compared to the controls, girls with central precocious puberty showed a delay in sleep timing of 54 min, and girls with premature pubarche slept on average 30 min later. Male adolescents with delayed pubertal development showed an average sleep midpoint that was 40 min earlier compared to the control group. The results of this pilot study suggest an association between pubertal onset and shifts in sleep timing, which is a novel finding in human sleep behavior. Prospective studies in larger cohorts will be needed to examine the robustness and generalizability of the findings.
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spelling pubmed-75096722020-10-20 Sleep Timing in Patients with Precocious and Delayed Pubertal Development Jessen, Elena Vetter, Celine Roenneberg, Till Liesenkötter, Klaus-Peter Werner, Helene Jenni, Oskar G. Lankes, Erwin Blankenstein, Oliver Neumann, Uta Köhler, Birgit Wiegand, Susanna Krude, Heiko Kühnen, Peter Clocks Sleep Article Previous studies have reported a shift in the timing of sleep during adolescence toward a later time. To date, it is unclear whether hormonal changes during puberty might contribute to this change in sleeping behavior. We systematically assessed pubertal development and sleep timing in a cross-sectional case-control study in girls with precocious (n = 42) and boys with delayed pubertal development (n = 19). We used the Munich ChronoType Questionnaire and the Children’s ChronoType Questionnaire to assess sleep timing in patients and age- and sex-matched controls (n = 309) and used the midpoint of sleep on free days, corrected for potential sleep debt accumulated during the school week, as a marker for sleep timing. Compared to the controls, girls with central precocious puberty showed a delay in sleep timing of 54 min, and girls with premature pubarche slept on average 30 min later. Male adolescents with delayed pubertal development showed an average sleep midpoint that was 40 min earlier compared to the control group. The results of this pilot study suggest an association between pubertal onset and shifts in sleep timing, which is a novel finding in human sleep behavior. Prospective studies in larger cohorts will be needed to examine the robustness and generalizability of the findings. MDPI 2019-02-16 /pmc/articles/PMC7509672/ /pubmed/33089160 http://dx.doi.org/10.3390/clockssleep1010013 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jessen, Elena
Vetter, Celine
Roenneberg, Till
Liesenkötter, Klaus-Peter
Werner, Helene
Jenni, Oskar G.
Lankes, Erwin
Blankenstein, Oliver
Neumann, Uta
Köhler, Birgit
Wiegand, Susanna
Krude, Heiko
Kühnen, Peter
Sleep Timing in Patients with Precocious and Delayed Pubertal Development
title Sleep Timing in Patients with Precocious and Delayed Pubertal Development
title_full Sleep Timing in Patients with Precocious and Delayed Pubertal Development
title_fullStr Sleep Timing in Patients with Precocious and Delayed Pubertal Development
title_full_unstemmed Sleep Timing in Patients with Precocious and Delayed Pubertal Development
title_short Sleep Timing in Patients with Precocious and Delayed Pubertal Development
title_sort sleep timing in patients with precocious and delayed pubertal development
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509672/
https://www.ncbi.nlm.nih.gov/pubmed/33089160
http://dx.doi.org/10.3390/clockssleep1010013
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