Potential effect of intravenous immunoglobulin against paraneoplastic cerebellar degeneration in progressive ovarian cancer

We report the effect of intravenous immunoglobulin (IVIG) against paraneoplastic cerebellar degeneration (PCD) in a case of progressive ovarian cancer. Our patient developed PCD soon after postoperative chemotherapy and became bedridden. After undergoing IVIG, however, symptoms dramatically improved...

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Detalles Bibliográficos
Autores principales: Shibata, Takashi, Oishi, Tetsuya, Fukuoka, Yasunori, Nishikawa, Shigeki, Iizuka, Noriaki, Kato, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509787/
https://www.ncbi.nlm.nih.gov/pubmed/33005721
http://dx.doi.org/10.1016/j.gore.2020.100649
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author Shibata, Takashi
Oishi, Tetsuya
Fukuoka, Yasunori
Nishikawa, Shigeki
Iizuka, Noriaki
Kato, Hiroki
author_facet Shibata, Takashi
Oishi, Tetsuya
Fukuoka, Yasunori
Nishikawa, Shigeki
Iizuka, Noriaki
Kato, Hiroki
author_sort Shibata, Takashi
collection PubMed
description We report the effect of intravenous immunoglobulin (IVIG) against paraneoplastic cerebellar degeneration (PCD) in a case of progressive ovarian cancer. Our patient developed PCD soon after postoperative chemotherapy and became bedridden. After undergoing IVIG, however, symptoms dramatically improved, and unexpectedly the remaining tumors were confirmed to have completely disappeared. When PCD is diagnosed, IVIG treatment should be attempted to reduce neuropathy regardless of its degree and the state of the cancer. It may also have further potential benefits that should be considered.
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spelling pubmed-75097872020-09-30 Potential effect of intravenous immunoglobulin against paraneoplastic cerebellar degeneration in progressive ovarian cancer Shibata, Takashi Oishi, Tetsuya Fukuoka, Yasunori Nishikawa, Shigeki Iizuka, Noriaki Kato, Hiroki Gynecol Oncol Rep Case Report We report the effect of intravenous immunoglobulin (IVIG) against paraneoplastic cerebellar degeneration (PCD) in a case of progressive ovarian cancer. Our patient developed PCD soon after postoperative chemotherapy and became bedridden. After undergoing IVIG, however, symptoms dramatically improved, and unexpectedly the remaining tumors were confirmed to have completely disappeared. When PCD is diagnosed, IVIG treatment should be attempted to reduce neuropathy regardless of its degree and the state of the cancer. It may also have further potential benefits that should be considered. Elsevier 2020-09-17 /pmc/articles/PMC7509787/ /pubmed/33005721 http://dx.doi.org/10.1016/j.gore.2020.100649 Text en © 2020 The Authors. Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Shibata, Takashi
Oishi, Tetsuya
Fukuoka, Yasunori
Nishikawa, Shigeki
Iizuka, Noriaki
Kato, Hiroki
Potential effect of intravenous immunoglobulin against paraneoplastic cerebellar degeneration in progressive ovarian cancer
title Potential effect of intravenous immunoglobulin against paraneoplastic cerebellar degeneration in progressive ovarian cancer
title_full Potential effect of intravenous immunoglobulin against paraneoplastic cerebellar degeneration in progressive ovarian cancer
title_fullStr Potential effect of intravenous immunoglobulin against paraneoplastic cerebellar degeneration in progressive ovarian cancer
title_full_unstemmed Potential effect of intravenous immunoglobulin against paraneoplastic cerebellar degeneration in progressive ovarian cancer
title_short Potential effect of intravenous immunoglobulin against paraneoplastic cerebellar degeneration in progressive ovarian cancer
title_sort potential effect of intravenous immunoglobulin against paraneoplastic cerebellar degeneration in progressive ovarian cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509787/
https://www.ncbi.nlm.nih.gov/pubmed/33005721
http://dx.doi.org/10.1016/j.gore.2020.100649
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