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Neonatal intestinal dysbiosis
The initial colonization of the neonatal intestinal tract is influenced by delivery mode, feeding, the maternal microbiota, and a host of environmental factors. After birth, the composition of the infant’s microbiota undergoes a series of significant changes particularly in the first weeks and month...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509828/ https://www.ncbi.nlm.nih.gov/pubmed/32968220 http://dx.doi.org/10.1038/s41372-020-00829-2 |
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author | Underwood, Mark A. Mukhopadhyay, Sagori Lakshminrusimha, Satyan Bevins, Charles L. |
author_facet | Underwood, Mark A. Mukhopadhyay, Sagori Lakshminrusimha, Satyan Bevins, Charles L. |
author_sort | Underwood, Mark A. |
collection | PubMed |
description | The initial colonization of the neonatal intestinal tract is influenced by delivery mode, feeding, the maternal microbiota, and a host of environmental factors. After birth, the composition of the infant’s microbiota undergoes a series of significant changes particularly in the first weeks and months of life ultimately developing into a more stable and diverse adult-like population in childhood. Intestinal dysbiosis is an alteration in the intestinal microbiota associated with disease and appears to be common in neonates. The consequences of intestinal dysbiosis are uncertain, but strong circumstantial evidence and limited confirmations of causality suggest that dysbiosis early in life can influence the health of the infant acutely, as well as contribute to disease susceptibility later in life. |
format | Online Article Text |
id | pubmed-7509828 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group US |
record_format | MEDLINE/PubMed |
spelling | pubmed-75098282020-09-23 Neonatal intestinal dysbiosis Underwood, Mark A. Mukhopadhyay, Sagori Lakshminrusimha, Satyan Bevins, Charles L. J Perinatol Review Article The initial colonization of the neonatal intestinal tract is influenced by delivery mode, feeding, the maternal microbiota, and a host of environmental factors. After birth, the composition of the infant’s microbiota undergoes a series of significant changes particularly in the first weeks and months of life ultimately developing into a more stable and diverse adult-like population in childhood. Intestinal dysbiosis is an alteration in the intestinal microbiota associated with disease and appears to be common in neonates. The consequences of intestinal dysbiosis are uncertain, but strong circumstantial evidence and limited confirmations of causality suggest that dysbiosis early in life can influence the health of the infant acutely, as well as contribute to disease susceptibility later in life. Nature Publishing Group US 2020-09-23 2020 /pmc/articles/PMC7509828/ /pubmed/32968220 http://dx.doi.org/10.1038/s41372-020-00829-2 Text en © The Author(s), under exclusive licence to Springer Nature America, Inc. 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Review Article Underwood, Mark A. Mukhopadhyay, Sagori Lakshminrusimha, Satyan Bevins, Charles L. Neonatal intestinal dysbiosis |
title | Neonatal intestinal dysbiosis |
title_full | Neonatal intestinal dysbiosis |
title_fullStr | Neonatal intestinal dysbiosis |
title_full_unstemmed | Neonatal intestinal dysbiosis |
title_short | Neonatal intestinal dysbiosis |
title_sort | neonatal intestinal dysbiosis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509828/ https://www.ncbi.nlm.nih.gov/pubmed/32968220 http://dx.doi.org/10.1038/s41372-020-00829-2 |
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