Cargando…

COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease

COVID-19 convalescent plasma (CP) may be a safe and effective treatment option in SARS-CoV-2 infection refractory to remdesivir. Infants may benefit from CP despite developing immune systems and donor variability emphasizes the need for characterization prior to use.

Detalles Bibliográficos
Autores principales: Rodriguez, Zahidee, Shane, Andi L., Verkerke, Hans, Lough, Christopher, Zimmerman, Matthew G., Suthar, Mehul, Wrammert, Jens, MacDonald, Heather, Wolf, Michael, Clarke, Shanelle, Roback, John D., Arthur, Connie M., Stowell, Sean R., Josephson, Cassandra D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509858/
https://www.ncbi.nlm.nih.gov/pubmed/32915971
http://dx.doi.org/10.1182/bloodadvances.2020002507
_version_ 1783585680783310848
author Rodriguez, Zahidee
Shane, Andi L.
Verkerke, Hans
Lough, Christopher
Zimmerman, Matthew G.
Suthar, Mehul
Wrammert, Jens
MacDonald, Heather
Wolf, Michael
Clarke, Shanelle
Roback, John D.
Arthur, Connie M.
Stowell, Sean R.
Josephson, Cassandra D.
author_facet Rodriguez, Zahidee
Shane, Andi L.
Verkerke, Hans
Lough, Christopher
Zimmerman, Matthew G.
Suthar, Mehul
Wrammert, Jens
MacDonald, Heather
Wolf, Michael
Clarke, Shanelle
Roback, John D.
Arthur, Connie M.
Stowell, Sean R.
Josephson, Cassandra D.
author_sort Rodriguez, Zahidee
collection PubMed
description COVID-19 convalescent plasma (CP) may be a safe and effective treatment option in SARS-CoV-2 infection refractory to remdesivir. Infants may benefit from CP despite developing immune systems and donor variability emphasizes the need for characterization prior to use.
format Online
Article
Text
id pubmed-7509858
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher American Society of Hematology
record_format MEDLINE/PubMed
spelling pubmed-75098582020-09-23 COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease Rodriguez, Zahidee Shane, Andi L. Verkerke, Hans Lough, Christopher Zimmerman, Matthew G. Suthar, Mehul Wrammert, Jens MacDonald, Heather Wolf, Michael Clarke, Shanelle Roback, John D. Arthur, Connie M. Stowell, Sean R. Josephson, Cassandra D. Blood Adv Exceptional Case Report COVID-19 convalescent plasma (CP) may be a safe and effective treatment option in SARS-CoV-2 infection refractory to remdesivir. Infants may benefit from CP despite developing immune systems and donor variability emphasizes the need for characterization prior to use. American Society of Hematology 2020-09-11 /pmc/articles/PMC7509858/ /pubmed/32915971 http://dx.doi.org/10.1182/bloodadvances.2020002507 Text en © 2020 by The American Society of Hematology This article is made available via the PMC Open Access Subset for unrestricted reuse and analyses in any form or by any means with acknowledgment of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle Exceptional Case Report
Rodriguez, Zahidee
Shane, Andi L.
Verkerke, Hans
Lough, Christopher
Zimmerman, Matthew G.
Suthar, Mehul
Wrammert, Jens
MacDonald, Heather
Wolf, Michael
Clarke, Shanelle
Roback, John D.
Arthur, Connie M.
Stowell, Sean R.
Josephson, Cassandra D.
COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease
title COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease
title_full COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease
title_fullStr COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease
title_full_unstemmed COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease
title_short COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease
title_sort covid-19 convalescent plasma clears sars-cov-2 refractory to remdesivir in an infant with congenital heart disease
topic Exceptional Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509858/
https://www.ncbi.nlm.nih.gov/pubmed/32915971
http://dx.doi.org/10.1182/bloodadvances.2020002507
work_keys_str_mv AT rodriguezzahidee covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT shaneandil covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT verkerkehans covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT loughchristopher covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT zimmermanmatthewg covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT sutharmehul covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT wrammertjens covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT macdonaldheather covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT wolfmichael covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT clarkeshanelle covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT robackjohnd covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT arthurconniem covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT stowellseanr covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease
AT josephsoncassandrad covid19convalescentplasmaclearssarscov2refractorytoremdesivirinaninfantwithcongenitalheartdisease