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Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage

Glucocorticoids are commonly used in the management of patients with brain Tumour for reducing peritumoral and vasogenic edema. However, they may lead to development of limb and life-threatening conditions such as necrotizing fasciitis (NF). NF is a rare but potentially lethal condition. Early detec...

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Autores principales: Johnson, Miguel, Berner, Juan, Christopoulos, George, Hamilton, Preci, Pearl, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509890/
https://www.ncbi.nlm.nih.gov/pubmed/32994923
http://dx.doi.org/10.1093/jscr/rjaa372
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author Johnson, Miguel
Berner, Juan
Christopoulos, George
Hamilton, Preci
Pearl, Robert
author_facet Johnson, Miguel
Berner, Juan
Christopoulos, George
Hamilton, Preci
Pearl, Robert
author_sort Johnson, Miguel
collection PubMed
description Glucocorticoids are commonly used in the management of patients with brain Tumour for reducing peritumoral and vasogenic edema. However, they may lead to development of limb and life-threatening conditions such as necrotizing fasciitis (NF). NF is a rare but potentially lethal condition. Early detection and aggressive treatment may lead to decreased mortality and limb salvage. The diagnosis is predominately clinical but may be supported by laboratory and radiological investigations. Chronic steroid use not only predisposes to the development of NF but also may mask early features delaying presentation and diagnosis. Clinicians should have a high index of suspicion especially in patients on chronic steroid therapy as this may aid in early detection and treatment. We present a case report of a successful limb salvage that exemplifies these points.
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spelling pubmed-75098902020-09-28 Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage Johnson, Miguel Berner, Juan Christopoulos, George Hamilton, Preci Pearl, Robert J Surg Case Rep Case Report Glucocorticoids are commonly used in the management of patients with brain Tumour for reducing peritumoral and vasogenic edema. However, they may lead to development of limb and life-threatening conditions such as necrotizing fasciitis (NF). NF is a rare but potentially lethal condition. Early detection and aggressive treatment may lead to decreased mortality and limb salvage. The diagnosis is predominately clinical but may be supported by laboratory and radiological investigations. Chronic steroid use not only predisposes to the development of NF but also may mask early features delaying presentation and diagnosis. Clinicians should have a high index of suspicion especially in patients on chronic steroid therapy as this may aid in early detection and treatment. We present a case report of a successful limb salvage that exemplifies these points. Oxford University Press 2020-09-23 /pmc/articles/PMC7509890/ /pubmed/32994923 http://dx.doi.org/10.1093/jscr/rjaa372 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2020. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Johnson, Miguel
Berner, Juan
Christopoulos, George
Hamilton, Preci
Pearl, Robert
Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage
title Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage
title_full Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage
title_fullStr Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage
title_full_unstemmed Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage
title_short Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage
title_sort fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: a case report of successful limb salvage
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509890/
https://www.ncbi.nlm.nih.gov/pubmed/32994923
http://dx.doi.org/10.1093/jscr/rjaa372
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