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Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage
Glucocorticoids are commonly used in the management of patients with brain Tumour for reducing peritumoral and vasogenic edema. However, they may lead to development of limb and life-threatening conditions such as necrotizing fasciitis (NF). NF is a rare but potentially lethal condition. Early detec...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509890/ https://www.ncbi.nlm.nih.gov/pubmed/32994923 http://dx.doi.org/10.1093/jscr/rjaa372 |
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author | Johnson, Miguel Berner, Juan Christopoulos, George Hamilton, Preci Pearl, Robert |
author_facet | Johnson, Miguel Berner, Juan Christopoulos, George Hamilton, Preci Pearl, Robert |
author_sort | Johnson, Miguel |
collection | PubMed |
description | Glucocorticoids are commonly used in the management of patients with brain Tumour for reducing peritumoral and vasogenic edema. However, they may lead to development of limb and life-threatening conditions such as necrotizing fasciitis (NF). NF is a rare but potentially lethal condition. Early detection and aggressive treatment may lead to decreased mortality and limb salvage. The diagnosis is predominately clinical but may be supported by laboratory and radiological investigations. Chronic steroid use not only predisposes to the development of NF but also may mask early features delaying presentation and diagnosis. Clinicians should have a high index of suspicion especially in patients on chronic steroid therapy as this may aid in early detection and treatment. We present a case report of a successful limb salvage that exemplifies these points. |
format | Online Article Text |
id | pubmed-7509890 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-75098902020-09-28 Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage Johnson, Miguel Berner, Juan Christopoulos, George Hamilton, Preci Pearl, Robert J Surg Case Rep Case Report Glucocorticoids are commonly used in the management of patients with brain Tumour for reducing peritumoral and vasogenic edema. However, they may lead to development of limb and life-threatening conditions such as necrotizing fasciitis (NF). NF is a rare but potentially lethal condition. Early detection and aggressive treatment may lead to decreased mortality and limb salvage. The diagnosis is predominately clinical but may be supported by laboratory and radiological investigations. Chronic steroid use not only predisposes to the development of NF but also may mask early features delaying presentation and diagnosis. Clinicians should have a high index of suspicion especially in patients on chronic steroid therapy as this may aid in early detection and treatment. We present a case report of a successful limb salvage that exemplifies these points. Oxford University Press 2020-09-23 /pmc/articles/PMC7509890/ /pubmed/32994923 http://dx.doi.org/10.1093/jscr/rjaa372 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2020. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Johnson, Miguel Berner, Juan Christopoulos, George Hamilton, Preci Pearl, Robert Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage |
title | Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage |
title_full | Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage |
title_fullStr | Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage |
title_full_unstemmed | Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage |
title_short | Fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: A case report of successful limb salvage |
title_sort | fulminant necrotizing fasciitis to the hand in a patient on high-dose steroids: a case report of successful limb salvage |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509890/ https://www.ncbi.nlm.nih.gov/pubmed/32994923 http://dx.doi.org/10.1093/jscr/rjaa372 |
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