Cargando…

Comparative transcriptomic profiling of myxomatous mitral valve disease in the cavalier King Charles spaniel

BACKGROUND: Almost all elderly dogs develop myxomatous mitral valve disease by the end of their life, but the cavalier King Charles spaniel (CKCS) has a heightened susceptibility, frequently resulting in death at a young age and suggesting that there is a genetic component to the condition in this b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Markby, G. R., Macrae, V. E., Corcoran, B. M., Summers, K. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509937/ https://www.ncbi.nlm.nih.gov/pubmed/32967675 http://dx.doi.org/10.1186/s12917-020-02542-w

Ejemplares similares

A Genomic Study of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels
por: Bionda, Arianna, et al.
Publicado: (2020)

Echocardiographic Evaluation of the Mitral Valve in Cavalier King Charles Spaniels
por: Bagardi, Mara, et al.
Publicado: (2020)

Genetic Variants at the Nebulette Locus Are Associated with Myxomatous Mitral Valve Disease Severity in Cavalier King Charles Spaniels
por: Mead, Sophie E., et al.
Publicado: (2022)

Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease
por: Reimann, Maria J., et al.
Publicado: (2021)

Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease
por: Christiansen, Liselotte B., et al.
Publicado: (2020)

Breeding Restrictions Decrease the Prevalence of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels over an 8‐ to 10‐Year Period
por: Birkegård, A.C., et al.
Publicado: (2016)

Depleted Myocardial Coenzyme Q10 in Cavalier King Charles Spaniels with Congestive Heart Failure Due to Myxomatous Mitral Valve Disease
por: Christiansen, Liselotte B., et al.
Publicado: (2021)

Clinical and Echocardiographic Findings in an Aged Population of Cavalier King Charles Spaniels
por: Prieto Ramos, Jorge, et al.
Publicado: (2021)

Myoclonus in older Cavalier King Charles Spaniels
por: Rotter, Carina, et al.
Publicado: (2022)

Circulating MiR-30b-5p is upregulated in Cavalier King Charles Spaniels affected by early myxomatous mitral valve disease
por: Bagardi, Mara, et al.
Publicado: (2022)

Comparative Transcriptomic Profiling and Gene Expression for Myxomatous Mitral Valve Disease in the Dog and Human
por: Markby, Greg R., et al.
Publicado: (2017)

The genetic consequences of dog breed formation—Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels
por: Axelsson, Erik, et al.
Publicado: (2021)

Evaluation of the Swedish breeding program for cavalier King Charles spaniels
por: Lundin, Tobias, et al.
Publicado: (2010)

Correction: The genetic consequences of dog breed formation—Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels
por: Axelsson, Erik, et al.
Publicado: (2022)

Medical infrared thermal imaging of syringomyelia in the Cavalier King Charles Spaniel
por: Larkin, M., et al.
Publicado: (2020)

Volume reduction of the jugular foramina in Cavalier King Charles Spaniels with syringomyelia
por: Schmidt, Martin Jürgen, et al.
Publicado: (2012)

Morphometric analysis of spinal cord termination in Cavalier King Charles Spaniels
por: Sparks, Courtney R., et al.
Publicado: (2019)

Comparison of the mitral valve morphologies of Cavalier King Charles Spaniels and dogs of other breeds using 3D transthoracic echocardiography
por: Menciotti, Giulio, et al.
Publicado: (2018)

Mitral Regurgitation Severity and Left Ventricular Systolic Dimension Predict Survival in Young Cavalier King Charles Spaniels
por: Reimann, M.J., et al.
Publicado: (2017)

Assessing the relative importance of health and conformation traits in the cavalier king Charles spaniel
por: Wijnrocx, Katrien, et al.
Publicado: (2018)

Erratum for Morphometric analysis of spinal cord termination in Cavalier King Charles Spaniels
Publicado: (2019)

Mechanical quantitative sensory testing in cavalier King Charles spaniels with and without syringomyelia
por: Hechler, Ashley C., et al.
Publicado: (2020)

Syringomyelia: determining risk and protective factors in the conformation of the Cavalier King Charles Spaniel dog
por: Mitchell, Thomas J, et al.
Publicado: (2014)

Corpus Callosotomy in 3 Cavalier King Charles Spaniel Dogs with Drug-Resistant Epilepsy
por: Asada, Rikako, et al.
Publicado: (2021)

Prevalence of disorders recorded in Cavalier King Charles Spaniels attending primary-care veterinary practices in England
por: Summers, Jennifer F, et al.
Publicado: (2015)

Three-dimensional kinematics of the craniocervical junction of Cavalier King Charles Spaniels compared to Chihuahuas and Labrador retrievers
por: Nickel, Mareike-Kristin, et al.
Publicado: (2023)

Influence of Morphometry on Echocardiographic Measurements in Cavalier King Charles Spaniels: An Inverse Probability Weighting Analysis
por: Bagardi, Mara, et al.
Publicado: (2021)

Pilot study of head conformation changes over time in the Cavalier King Charles spaniel breed
por: Knowler, Susan Penelope, et al.
Publicado: (2019)

Investigation of sensory thresholds in Cavalier King Charles Spaniels with and without Chiari‐like malformations and syringomyelia
por: Sparks, Courtney R., et al.
Publicado: (2018)

Ventriculomegaly in Cavalier King Charles Spaniels with Chiari-like malformation: relationship with clinical and imaging findings
por: TIRRITO, Federica, et al.
Publicado: (2022)

Changes over time in craniocerebral morphology and syringomyelia in cavalier King Charles spaniels with Chiari-like malformation
por: Driver, Colin J, et al.
Publicado: (2012)

Disease Severity-Associated Gene Expression in Canine Myxomatous Mitral Valve Disease Is Dominated by TGFβ Signaling
por: Markby, Greg R., et al.
Publicado: (2020)

Medullary Position at the Craniocervical Junction in Mature Cavalier King Charles Spaniels: Relationship with Neurologic Signs and Syringomyelia
por: Cerda‐Gonzalez, S., et al.
Publicado: (2015)

Degenerative Valvular Disease in the Cavalier King Charles Spaniel: Results of the UK Breed Scheme 1991–2010
por: Swift, S., et al.
Publicado: (2017)

Behavioral and clinical signs of Chiari‐like malformation‐associated pain and syringomyelia in Cavalier King Charles spaniels
por: Rusbridge, Clare, et al.
Publicado: (2019)

Association between filum terminale internum length and pain in Cavalier King Charles spaniels with and without syringomyelia
por: Sparks, Courtney R., et al.
Publicado: (2021)

Prospective pilot study on the predictive significance of plasma miR-30b-5p through the study of echocardiographic modifications in Cavalier King Charles Spaniels affected by different stages of myxomatous mitral valve disease: The PRIME study
por: Ghilardi, Sara, et al.
Publicado: (2022)

Prevalence and Heritability of Symptomatic Syringomyelia in Cavalier King Charles Spaniels and Long‐term Outcome in Symptomatic and Asymptomatic Littermates
por: Thøfner, M.S., et al.
Publicado: (2014)

Increase in Cerebellar Volume in Cavalier King Charles Spaniels with Chiari-like Malformation and Its Role in the Development of Syringomyelia
por: Shaw, Thomas A., et al.
Publicado: (2012)

Evaluation of canine 2D cell cultures as models of myxomatous mitral valve degeneration
por: Tan, Karen, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4mgllba0u8dhi5svefo67mhjkn