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Vascular NRP2 triggers PNET angiogenesis by activating the SSH1-cofilin axis

BACKGROUND: Angiogenesis is a critical step in the growth of pancreatic neuroendocrine tumors (PNETs) and may be a selective target for PNET therapy. However, PNETs are robustly resistant to current anti-angiogenic therapies that primarily target the VEGFR pathway. Thus, the mechanism of PNET angiog...

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Detalles Bibliográficos
Autores principales: Luo, Xi, He, Jiang-yi, Xu, Jie, Hu, Shao-yi, Mo, Bang-hui, Shu, Qiu-xia, Chen, Can, Gong, Yu-zhu, Zhao, Xiao-long, Xie, Gan-feng, Yu, Song-tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509939/
https://www.ncbi.nlm.nih.gov/pubmed/32983407
http://dx.doi.org/10.1186/s13578-020-00472-6