Cargando…
Vascular NRP2 triggers PNET angiogenesis by activating the SSH1-cofilin axis
BACKGROUND: Angiogenesis is a critical step in the growth of pancreatic neuroendocrine tumors (PNETs) and may be a selective target for PNET therapy. However, PNETs are robustly resistant to current anti-angiogenic therapies that primarily target the VEGFR pathway. Thus, the mechanism of PNET angiog...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509939/ https://www.ncbi.nlm.nih.gov/pubmed/32983407 http://dx.doi.org/10.1186/s13578-020-00472-6 |