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Vascular NRP2 triggers PNET angiogenesis by activating the SSH1-cofilin axis
BACKGROUND: Angiogenesis is a critical step in the growth of pancreatic neuroendocrine tumors (PNETs) and may be a selective target for PNET therapy. However, PNETs are robustly resistant to current anti-angiogenic therapies that primarily target the VEGFR pathway. Thus, the mechanism of PNET angiog...
Autores principales: | Luo, Xi, He, Jiang-yi, Xu, Jie, Hu, Shao-yi, Mo, Bang-hui, Shu, Qiu-xia, Chen, Can, Gong, Yu-zhu, Zhao, Xiao-long, Xie, Gan-feng, Yu, Song-tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509939/ https://www.ncbi.nlm.nih.gov/pubmed/32983407 http://dx.doi.org/10.1186/s13578-020-00472-6 |
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