Polymorphisms in Inflammatory Genes Modulate Clinical Complications in Patients With Sickle Cell Disease

Sickle cell disease (SCD), the most common monogenic disease worldwide, is marked by a phenotypic variability that is, to date, only partially understood. Because inflammation plays a major role in SCD pathophysiology, we hypothesized that single nucleotide polymorphisms (SNP) in genes encoding func...

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Detalles Bibliográficos
Autores principales: Tozatto-Maio, Karina, Girot, Robert, Ly, Indou Deme, Silva Pinto, Ana Cristina, Rocha, Vanderson, Fernandes, Francisco, Diagne, Ibrahima, Benzerara, Yahia, Dinardo, Carla L., Soler, Julia Pavan, Kashima, Simone, Araujo, Itauá Leston, Kenzey, Chantal, Fonseca, Guilherme H. H., Rodrigues, Evandra S., Volt, Fernanda, Jarduli, Luciana, Ruggeri, Annalisa, Mariaselvam, Christina, Gualandro, Sandra F. M., Rafii, Hanadi, Cappelli, Barbara, Nogueira, Felipe Melo, Scigliuolo, Graziana Maria, Guerino-Cunha, Renato Luiz, Malmegrim, Kelen Cristina Ribeiro, Simões, Belinda P., Gluckman, Eliane, Tamouza, Ryad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510050/
https://www.ncbi.nlm.nih.gov/pubmed/33013863
http://dx.doi.org/10.3389/fimmu.2020.02041

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