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Somatic mutation detection efficiency in EGFR: a comparison between high resolution melting analysis and Sanger sequencing

BACKGROUND: High resolution melting curve analysis is a cost-effective rapid screening method for detection of somatic gene mutation. The performance characteristics of this technique has been explored previously, however, analytical parameters such as limit of detection of mutant allele fraction an...

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Detalles Bibliográficos
Autores principales:	Joy, Reenu Anne, Thelakkattusserry, Sukrishna Kamalasanan, Vikkath, Narendranath, Bhaskaran, Renjitha, Krishnan, Sajitha, Vasudevan, Damodaran, Ariyannur, Prasanth S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510081/ https://www.ncbi.nlm.nih.gov/pubmed/32962681 http://dx.doi.org/10.1186/s12885-020-07411-1

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