Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway

BACKGROUND: Autophagy is an intracellular process through which intracellular components are recycled in response to nutrient or growth factor deficiency to maintain homeostasis. We identified the peptide autophagy-related cancer-suppressing peptide (ARCSP), a potential antitumor peptide that disrup...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yang, Wang, Qi, Song, Dongjian, Zen, Ruirui, Zhang, Lei, Wang, Yingjun, Yang, Heying, Zhang, Da, Jia, Jia, Zhang, Jiao, Wang, Jiaxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510096/
https://www.ncbi.nlm.nih.gov/pubmed/32962728
http://dx.doi.org/10.1186/s13046-020-01701-z

Ejemplares similares

Ejemplares similares