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The importance of expert review to clarify ambiguous situations for (Q)SAR predictions under ICH M7

The use of in silico predictions for the assessment of bacterial mutagenicity under the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) M7 guideline is recommended when two complementary (quantitative) structure-activity relationship (Q)SAR m...

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Detalles Bibliográficos
Autores principales: Foster, Robert S., Fowkes, Adrian, Cayley, Alex, Thresher, Andrew, Werner, Anne-Laure D., Barber, Chris G., Kocks, Grace, Tennant, Rachael E., Williams, Richard V., Kane, Steven, Stalford, Susanne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510098/
https://www.ncbi.nlm.nih.gov/pubmed/32983286
http://dx.doi.org/10.1186/s41021-020-00166-y