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Considering the societal perspective in economic evaluations: a systematic review in the case of depression
BACKGROUND: Depressive disorders are associated with a high burden of disease. However, due to the burden posed by the disease on not only the sufferers, but also on their relatives, there is an ongoing debate about which costs to include and, hence, which perspective should be applied. Therefore, t...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510122/ https://www.ncbi.nlm.nih.gov/pubmed/32964372 http://dx.doi.org/10.1186/s13561-020-00288-7 |
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author | Duevel, Juliane Andrea Hasemann, Lena Peña-Longobardo, Luz María Rodríguez-Sánchez, Beatriz Aranda-Reneo, Isaac Oliva-Moreno, Juan López-Bastida, Julio Greiner, Wolfgang |
author_facet | Duevel, Juliane Andrea Hasemann, Lena Peña-Longobardo, Luz María Rodríguez-Sánchez, Beatriz Aranda-Reneo, Isaac Oliva-Moreno, Juan López-Bastida, Julio Greiner, Wolfgang |
author_sort | Duevel, Juliane Andrea |
collection | PubMed |
description | BACKGROUND: Depressive disorders are associated with a high burden of disease. However, due to the burden posed by the disease on not only the sufferers, but also on their relatives, there is an ongoing debate about which costs to include and, hence, which perspective should be applied. Therefore, the aim of this paper was to examine whether the change between healthcare payer and societal perspective leads to different conclusions of cost-utility analyses in the case of depression. METHODS: A systematic literature search was conducted to identify economic evaluations of interventions in depression, launched on Medline and the Cost-Effectiveness Registry of the Tufts University using a ten-year time horizon (2008–2018). In a two-stepped screening process, cost-utility studies were selected by means of specified inclusion and exclusion criteria. Subsequently, relevant findings was extracted and, if not fully stated, calculated by the authors of this work. RESULTS: Overall, 53 articles with 92 complete economic evaluations, reporting costs from healthcare payer/provider and societal perspective, were identified. More precisely, 22 estimations (24%) changed their results regarding the cost-effectiveness quadrant when the societal perspective was included. Furthermore, 5% of the ICURs resulted in cost-effectiveness regarding the chosen threshold (2% of them became dominant) when societal costs were included. However, another four estimations (4%) showed the opposite result: these interventions were no longer cost-effective after the inclusion of societal costs. CONCLUSIONS: Summarising the disparities in results and applied methods, the results show that societal costs might alter the conclusions in cost-utility analyses. Hence, the relevance of the perspectives chosen should be taken into account when carrying out an economic evaluation. This systematic review demonstrates that the results of economic evaluations can be affected by different methods available for estimating non-healthcare costs. |
format | Online Article Text |
id | pubmed-7510122 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-75101222020-09-24 Considering the societal perspective in economic evaluations: a systematic review in the case of depression Duevel, Juliane Andrea Hasemann, Lena Peña-Longobardo, Luz María Rodríguez-Sánchez, Beatriz Aranda-Reneo, Isaac Oliva-Moreno, Juan López-Bastida, Julio Greiner, Wolfgang Health Econ Rev Review BACKGROUND: Depressive disorders are associated with a high burden of disease. However, due to the burden posed by the disease on not only the sufferers, but also on their relatives, there is an ongoing debate about which costs to include and, hence, which perspective should be applied. Therefore, the aim of this paper was to examine whether the change between healthcare payer and societal perspective leads to different conclusions of cost-utility analyses in the case of depression. METHODS: A systematic literature search was conducted to identify economic evaluations of interventions in depression, launched on Medline and the Cost-Effectiveness Registry of the Tufts University using a ten-year time horizon (2008–2018). In a two-stepped screening process, cost-utility studies were selected by means of specified inclusion and exclusion criteria. Subsequently, relevant findings was extracted and, if not fully stated, calculated by the authors of this work. RESULTS: Overall, 53 articles with 92 complete economic evaluations, reporting costs from healthcare payer/provider and societal perspective, were identified. More precisely, 22 estimations (24%) changed their results regarding the cost-effectiveness quadrant when the societal perspective was included. Furthermore, 5% of the ICURs resulted in cost-effectiveness regarding the chosen threshold (2% of them became dominant) when societal costs were included. However, another four estimations (4%) showed the opposite result: these interventions were no longer cost-effective after the inclusion of societal costs. CONCLUSIONS: Summarising the disparities in results and applied methods, the results show that societal costs might alter the conclusions in cost-utility analyses. Hence, the relevance of the perspectives chosen should be taken into account when carrying out an economic evaluation. This systematic review demonstrates that the results of economic evaluations can be affected by different methods available for estimating non-healthcare costs. Springer Berlin Heidelberg 2020-09-22 /pmc/articles/PMC7510122/ /pubmed/32964372 http://dx.doi.org/10.1186/s13561-020-00288-7 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Review Duevel, Juliane Andrea Hasemann, Lena Peña-Longobardo, Luz María Rodríguez-Sánchez, Beatriz Aranda-Reneo, Isaac Oliva-Moreno, Juan López-Bastida, Julio Greiner, Wolfgang Considering the societal perspective in economic evaluations: a systematic review in the case of depression |
title | Considering the societal perspective in economic evaluations: a systematic review in the case of depression |
title_full | Considering the societal perspective in economic evaluations: a systematic review in the case of depression |
title_fullStr | Considering the societal perspective in economic evaluations: a systematic review in the case of depression |
title_full_unstemmed | Considering the societal perspective in economic evaluations: a systematic review in the case of depression |
title_short | Considering the societal perspective in economic evaluations: a systematic review in the case of depression |
title_sort | considering the societal perspective in economic evaluations: a systematic review in the case of depression |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510122/ https://www.ncbi.nlm.nih.gov/pubmed/32964372 http://dx.doi.org/10.1186/s13561-020-00288-7 |
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