Cargando…

AEB-071 Ameliorates Muscle Weakness by Altering Helper T Lymphocytes in an Experimental Autoimmune Myasthenia Gravis Rat Model

BACKGROUND: Myasthenia gravis (MG) is an autoimmune neurological disorder of neuromuscular junctions. In this study we established experimental autoimmune myasthenia gravis (EAMG) rat models to investigate the effects of AEB-071 (AEB), which is a specific inhibitor of protein kinase C that prevents...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jing, Feng, Huang, Wei, Ma, Qian, Xu, Sheng-jie, Wu, Chang-jin, Guan, Yu-xiu, Chen, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2020
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510173/ https://www.ncbi.nlm.nih.gov/pubmed/32920588 http://dx.doi.org/10.12659/MSM.924393

Ejemplares similares

CXCR5-negative natural killer cells ameliorate experimental autoimmune myasthenia gravis by suppressing follicular helper T cells
por: Yang, Chun-Lin, et al.
Publicado: (2019)

miR-15b is Downregulated in Myasthenia Gravis Patients and Directly Regulates the Expression of Interleukin-15 (IL-15) in Experimental Myasthenia Gravis Mice
por: Shi, Lei, et al.
Publicado: (2015)

Experimental autoimmune myasthenia gravis and CD5+ B-lymphocyte expression.
por: Lee, K. W., et al.
Publicado: (1999)

Autoimmune Thyroiditis and Myasthenia Gravis
por: Lopomo, Angela, et al.
Publicado: (2017)

Inflammation and autoimmune myasthenia gravis
por: Huda, Ruksana
Publicado: (2023)

Astragaloside IV ameliorates experimental autoimmune myasthenia gravis by regulating CD4 + T cells and altering gut microbiota
por: Weng, Senhui, et al.
Publicado: (2023)

Classification of myasthenia gravis and congenital myasthenic syndromes in dogs and cats
por: Mignan, Thomas, et al.
Publicado: (2020)

Clinical features and outcome of acquired myasthenia gravis in 94 dogs
por: Forgash, Jennifer T., et al.
Publicado: (2021)

Risk Factors and Outcomes in Cats with Acquired Myasthenia Gravis (2001–2012)
por: Hague, D.W., et al.
Publicado: (2015)

Editorial: Advances in Autoimmune Myasthenia Gravis
por: Punga, Anna Rostedt, et al.
Publicado: (2020)

Role of complement in the pathogenesis of experimental autoimmune myasthenia gravis
Publicado: (1978)

Experimental autoimmune myasthenia: A model of myasthenia gravis in rats and guinea pigs
Publicado: (1975)

Pathological mechanisms in experimental autoimmune myasthenia gravis. II. Passive transfer of experimental autoimmune myasthenia gravis in rats with anti-acetylcholine recepotr antibodies
Publicado: (1976)

Alteration in gene expression profile of thymomas with or without myasthenia gravis linked with the nuclear factor‐kappaB/autoimmune regulator pathway to myasthenia gravis pathogenesis
por: Guo, Feng, et al.
Publicado: (2019)

Fatigue in myasthenia gravis: is it more than muscular weakness?
por: Elsais, Ahmed, et al.
Publicado: (2013)

Misdiagnosis of myasthenia gravis presenting with tongue and palatal weakness
por: Marshal, Megan, et al.
Publicado: (2018)

Sensitivity of MG‐ADL for generalized weakness in myasthenia gravis
por: de Meel, R. H. P., et al.
Publicado: (2018)

Prophylactic Effect of Probiotics on the Development of Experimental Autoimmune Myasthenia Gravis
por: Chae, Chang-Suk, et al.
Publicado: (2012)

Autoimmune Myasthenia Gravis after Sternal Fracture
por: Petersen, Jens A., et al.
Publicado: (2012)

Statin-associated weakness in myasthenia gravis: a case report
por: Keogh, Michael J, et al.
Publicado: (2010)

Altered Gut Microbiota in Myasthenia Gravis
por: Qiu, Dongxu, et al.
Publicado: (2018)

Long‐term outcome of cats with acquired myasthenia gravis without evidence of a cranial mediastinal mass
por: Mignan, Thomas, et al.
Publicado: (2019)

Immune Skew of Circulating Follicular Helper T Cells Associates With Myasthenia Gravis Severity
por: Ashida, Shinji, et al.
Publicado: (2021)

B-Cell-Activating Factor and Autoimmune Myasthenia Gravis
por: Ragheb, Samia, et al.
Publicado: (2011)

Complicating autoimmune diseases in myasthenia gravis: a review
por: Nacu, Aliona, et al.
Publicado: (2015)

New Pathways and Therapeutic Targets in Autoimmune Myasthenia Gravis
por: Behin, Anthony, et al.
Publicado: (2018)

Myasthenia Gravis Impairment Index: Sensitivity for Change in Generalized Muscle Weakness
por: de Meel, Robert H.P., et al.
Publicado: (2020)

Myasthenia gravis
por: Juel, Vern C, et al.
Publicado: (2007)

Myasthenia Gravis
por: Aarli, Johan A., et al.
Publicado: (2011)

Myasthenia Gravis
Publicado: (1905)

Myasthenia Gravis
por: Wilson, Andrew
Publicado: (1952)

Myasthenia Gravis
por: Bramwell, Edwin
Publicado: (1901)

Therapeutic Effect of Bifidobacterium Administration on Experimental Autoimmune Myasthenia Gravis in Lewis Rats
por: Rinaldi, Elena, et al.
Publicado: (2019)

Whole-Genome Analysis in Korean Patients with Autoimmune Myasthenia Gravis
por: Na, Sang-Jun, et al.
Publicado: (2014)

Prevalence and impact of autoimmune thyroid disease on myasthenia gravis course
por: Kubiszewska, Justyna, et al.
Publicado: (2016)

Autoimmunity strikes neuromuscular junction: Myasthenia gravis & achalasia cardia
por: Sulena,, et al.
Publicado: (2020)

Statin‐associated necrotizing autoimmune myopathy with concurrent myasthenia gravis
por: Frasson, Emma, et al.
Publicado: (2021)

Clinical features of myasthenia gravis with neurological and systemic autoimmune diseases
por: Zhu, Ying, et al.
Publicado: (2023)

Caspase-1 inhibitor ameliorates experimental autoimmune myasthenia gravis by innate dendric cell IL-1-IL-17 pathway
por: Wang, Cong-Cong, et al.
Publicado: (2015)

Effect of Grilled Nux Vomica on Differential RNA Expression Profile of Gastrocnemius Muscle and Toll-Like Receptor 4 (TLR-4)/Nuclear Factor kappa B (NF-κB) Signaling in Experimental Autoimmune Myasthenia Gravis Rats
por: Jiang, Xu Hong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9d90h397lvpnaskv4le8sbab5a