Cargando…
In vivo animal models confirm an increased virulence potential and pathogenicity of the NAP1/RT027/ST01 genotype within the Clostridium difficile MLST Clade 2
BACKGROUND: Based on MLST analyses the global population of C. difficile is distributed in eight clades, of which Clade 2 includes the “hypervirulent” NAP1/RT027/ST01 strain along with various unexplored sequence types (STs). METHODS: To clarify whether this clinically relevant phenotype is a widesp...
Autores principales: | Orozco-Aguilar, Josué, Alfaro-Alarcón, Alejandro, Acuña-Amador, Luis, Chaves-Olarte, Esteban, Rodríguez, César, Quesada-Gómez, Carlos |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510272/ https://www.ncbi.nlm.nih.gov/pubmed/32983262 http://dx.doi.org/10.1186/s13099-020-00383-4 |
Ejemplares similares
-
Origin, genomic diversity and microevolution of the Clostridium difficile B1/NAP1/RT027/ST01 strain in Costa Rica, Chile, Honduras and Mexico
por: Guerrero-Araya, Enzo, et al.
Publicado: (2020) -
Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors
por: López-Ureña, Diana, et al.
Publicado: (2019) -
Reconsidering the Sporulation Characteristics of Hypervirulent Clostridium difficile BI/NAP1/027
por: Burns, David A., et al.
Publicado: (2011) -
First Report of Clostridium difficile NAP1/027 in a Mexican Hospital
por: Camacho-Ortiz, Adrián, et al.
Publicado: (2015) -
Clostridium difficile outbreak caused by NAP1/BI/027 strain and non-027 strains in a Mexican hospital
por: Morfin-Otero, Rayo, et al.
Publicado: (2015)