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Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–2018
We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy–naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically l...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Centers for Disease Control and Prevention
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510719/ https://www.ncbi.nlm.nih.gov/pubmed/32946725 http://dx.doi.org/10.3201/eid2610.191506 |
| _version_ | 1783585849703661568 |
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| author | Stecher, Melanie Chaillon, Antoine Stephan, Christoph Knops, Elena Kohmer, Niko Lehmann, Clara Eberle, Josef Bogner, Johannes Spinner, Christoph D. Eis-Hübinger, Anna Maria Wasmuth, Jan-Christian Schäfer, Guido Behrens, Georg Mehta, Sanjay R. Vehreschild, Jörg Janne Hoenigl, Martin |
| author_facet | Stecher, Melanie Chaillon, Antoine Stephan, Christoph Knops, Elena Kohmer, Niko Lehmann, Clara Eberle, Josef Bogner, Johannes Spinner, Christoph D. Eis-Hübinger, Anna Maria Wasmuth, Jan-Christian Schäfer, Guido Behrens, Georg Mehta, Sanjay R. Vehreschild, Jörg Janne Hoenigl, Martin |
| author_sort | Stecher, Melanie |
| collection | PubMed |
| description | We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy–naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically linked patients; K103N was the most frequently shared mutation. |
| format | Online Article Text |
| id | pubmed-7510719 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Centers for Disease Control and Prevention |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-75107192020-10-02 Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–2018 Stecher, Melanie Chaillon, Antoine Stephan, Christoph Knops, Elena Kohmer, Niko Lehmann, Clara Eberle, Josef Bogner, Johannes Spinner, Christoph D. Eis-Hübinger, Anna Maria Wasmuth, Jan-Christian Schäfer, Guido Behrens, Georg Mehta, Sanjay R. Vehreschild, Jörg Janne Hoenigl, Martin Emerg Infect Dis Dispatch We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy–naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically linked patients; K103N was the most frequently shared mutation. Centers for Disease Control and Prevention 2020-10 /pmc/articles/PMC7510719/ /pubmed/32946725 http://dx.doi.org/10.3201/eid2610.191506 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
| spellingShingle | Dispatch Stecher, Melanie Chaillon, Antoine Stephan, Christoph Knops, Elena Kohmer, Niko Lehmann, Clara Eberle, Josef Bogner, Johannes Spinner, Christoph D. Eis-Hübinger, Anna Maria Wasmuth, Jan-Christian Schäfer, Guido Behrens, Georg Mehta, Sanjay R. Vehreschild, Jörg Janne Hoenigl, Martin Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–2018 |
| title | Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–2018 |
| title_full | Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–2018 |
| title_fullStr | Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–2018 |
| title_full_unstemmed | Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–2018 |
| title_short | Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–2018 |
| title_sort | drug resistance spread in 6 metropolitan regions, germany, 2001–2018 |
| topic | Dispatch |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510719/ https://www.ncbi.nlm.nih.gov/pubmed/32946725 http://dx.doi.org/10.3201/eid2610.191506 |
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