Sequential Acquisition of Human Papillomavirus Infection at Genital and Anal Sites, Liuzhou, China

Little is known about the risk for acquiring a concordant human papillomavirus (HPV) infection in a genital (or anal) site after an anal (or genital) HPV infection. We collected 3 sets of anogenital specimens at 6-month intervals from 2,309 men and 2,378 women in Liuzhou, China, and tested these spe...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Feixue, Su, Yingying, Cui, Xuelian, Yu, Xiaojuan, Li, Yafei, Song, Qiaoqiao, Yin, Kai, Huang, Shoujie, Li, Mingqiang, Zhang, Jun, Wu, Ting, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510729/
https://www.ncbi.nlm.nih.gov/pubmed/32946717
http://dx.doi.org/10.3201/eid2610.191646
Descripción
Sumario:Little is known about the risk for acquiring a concordant human papillomavirus (HPV) infection in a genital (or anal) site after an anal (or genital) HPV infection. We collected 3 sets of anogenital specimens at 6-month intervals from 2,309 men and 2,378 women in Liuzhou, China, and tested these specimens for HPV. The risk for sequential anal HPV infection in participants with a previous genital HPV infection was higher than for participants without an infection (hazard ratio [HR] 4.4, 95% CI 3.4–5.8 for women and HR 2.6, 95% CI 1.4–4.6 for men). For sequential genital HPV infection, women with a previous anal infection had a higher risk (HR 1.9, 95% CI 1.2–3.1), but no major difference was found for men (HR 0.7, 95% CI 0.2–1.9). Our study indicates that autoinoculation might play a major role in anogenital HPV transmission, in addition to direct sexual intercourse, especially for anal infection in women.

Ejemplares similares