Cargando…

Usability of graphene oxide as a mycotoxin binder: In vitro study

Mycotoxin management in agriculture is an essential challenge for maintaining the health of both animals and humans. Choosing the right adsorbent is still a question for many breeders and an important criterion for feed manufacturers. New adsorbents are still being sought. Graphene oxide is a promis...

Descripción completa

Detalles Bibliográficos
Autores principales: Horky, Pavel, Venusova, Eva, Aulichova, Tereza, Ridoskova, Andrea, Skladanka, Jiri, Skalickova, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510967/
https://www.ncbi.nlm.nih.gov/pubmed/32966310
http://dx.doi.org/10.1371/journal.pone.0239479
_version_ 1783585884470247424
author Horky, Pavel
Venusova, Eva
Aulichova, Tereza
Ridoskova, Andrea
Skladanka, Jiri
Skalickova, Sylvie
author_facet Horky, Pavel
Venusova, Eva
Aulichova, Tereza
Ridoskova, Andrea
Skladanka, Jiri
Skalickova, Sylvie
author_sort Horky, Pavel
collection PubMed
description Mycotoxin management in agriculture is an essential challenge for maintaining the health of both animals and humans. Choosing the right adsorbent is still a question for many breeders and an important criterion for feed manufacturers. New adsorbents are still being sought. Graphene oxide is a promising material in the field of nanotechnology, which excels in its adsorption properties. Presented in vitro study investigates graphene oxide for the binding of mycotoxins from crushed wheat. The results show that graphene oxide has an adsorption capacity for aflatoxin 0.045 mg/g, zearalenone 0.53 mg/g and deoxynivalenol 1.69 mg/g at 37° C. In vitro simulation of crushed wheat digestion showed rapid adsorption during the gastric phase. Of the minerals, Mg, Cu and Zn were the most adsorbed. The applied dose of graphene oxide of 10 mg/g caused only a slight inhibition of the digestive enzymes α-amylase and trypsin compared to pepsin and gastric lipase. In vitro results indicated the suitability of graphene oxide in the adsorption of the aflatoxin, zearalenone and deoxynivalenol.
format Online
Article
Text
id pubmed-7510967
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-75109672020-10-01 Usability of graphene oxide as a mycotoxin binder: In vitro study Horky, Pavel Venusova, Eva Aulichova, Tereza Ridoskova, Andrea Skladanka, Jiri Skalickova, Sylvie PLoS One Research Article Mycotoxin management in agriculture is an essential challenge for maintaining the health of both animals and humans. Choosing the right adsorbent is still a question for many breeders and an important criterion for feed manufacturers. New adsorbents are still being sought. Graphene oxide is a promising material in the field of nanotechnology, which excels in its adsorption properties. Presented in vitro study investigates graphene oxide for the binding of mycotoxins from crushed wheat. The results show that graphene oxide has an adsorption capacity for aflatoxin 0.045 mg/g, zearalenone 0.53 mg/g and deoxynivalenol 1.69 mg/g at 37° C. In vitro simulation of crushed wheat digestion showed rapid adsorption during the gastric phase. Of the minerals, Mg, Cu and Zn were the most adsorbed. The applied dose of graphene oxide of 10 mg/g caused only a slight inhibition of the digestive enzymes α-amylase and trypsin compared to pepsin and gastric lipase. In vitro results indicated the suitability of graphene oxide in the adsorption of the aflatoxin, zearalenone and deoxynivalenol. Public Library of Science 2020-09-23 /pmc/articles/PMC7510967/ /pubmed/32966310 http://dx.doi.org/10.1371/journal.pone.0239479 Text en © 2020 Horky et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Horky, Pavel
Venusova, Eva
Aulichova, Tereza
Ridoskova, Andrea
Skladanka, Jiri
Skalickova, Sylvie
Usability of graphene oxide as a mycotoxin binder: In vitro study
title Usability of graphene oxide as a mycotoxin binder: In vitro study
title_full Usability of graphene oxide as a mycotoxin binder: In vitro study
title_fullStr Usability of graphene oxide as a mycotoxin binder: In vitro study
title_full_unstemmed Usability of graphene oxide as a mycotoxin binder: In vitro study
title_short Usability of graphene oxide as a mycotoxin binder: In vitro study
title_sort usability of graphene oxide as a mycotoxin binder: in vitro study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510967/
https://www.ncbi.nlm.nih.gov/pubmed/32966310
http://dx.doi.org/10.1371/journal.pone.0239479
work_keys_str_mv AT horkypavel usabilityofgrapheneoxideasamycotoxinbinderinvitrostudy
AT venusovaeva usabilityofgrapheneoxideasamycotoxinbinderinvitrostudy
AT aulichovatereza usabilityofgrapheneoxideasamycotoxinbinderinvitrostudy
AT ridoskovaandrea usabilityofgrapheneoxideasamycotoxinbinderinvitrostudy
AT skladankajiri usabilityofgrapheneoxideasamycotoxinbinderinvitrostudy
AT skalickovasylvie usabilityofgrapheneoxideasamycotoxinbinderinvitrostudy