CRISPR-CBEI: a Designing and Analyzing Tool Kit for Cytosine Base Editor-Mediated Gene Inactivation

Base editing is a promising technique, allowing precise single-base mutagenesis in genomes without double-strand DNA breaks or donor templates. Cytosine base editors (CBEs) convert cytosine to thymidine. In particular, CBEs can transform four codons, CAA, CAG, CGA, and TGG, into stop codons, providi...

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Detalles Bibliográficos
Autores principales: Yu, Haopeng, Wu, Zhaowei, Chen, Xiangdan, Ji, Quanjiang, Tao, Shiheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511213/
https://www.ncbi.nlm.nih.gov/pubmed/32963098
http://dx.doi.org/10.1128/mSystems.00350-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511213/
https://www.ncbi.nlm.nih.gov/pubmed/32963098
http://dx.doi.org/10.1128/mSystems.00350-20

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