Atg1 kinase in fission yeast is activated by Atg11-mediated dimerization and cis-autophosphorylation

Autophagy is a proteolytic pathway that is conserved from yeasts to mammals. Atg1 kinase is essential for autophagy, but how its activity is controlled remains insufficiently understood. Here, we show that, in the fission yeast Schizosaccharomyces pombe, Atg1 kinase activity requires Atg11, the orth...

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Detalles Bibliográficos
Autores principales: Pan, Zhao-Qian, Shao, Guang-Can, Liu, Xiao-Man, Chen, Quan, Dong, Meng-Qiu, Du, Li-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511232/
https://www.ncbi.nlm.nih.gov/pubmed/32909946
http://dx.doi.org/10.7554/eLife.58073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511232/
https://www.ncbi.nlm.nih.gov/pubmed/32909946
http://dx.doi.org/10.7554/eLife.58073

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